Comparison of daclatasvir resistance barriers on NS5A from hepatitis C virus genotypes 1 to 6: implications for cross-genotype activity. (Q42109722)

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20 March 2020

title

Comparison of daclatasvir resistance barriers on NS5A from hepatitis C virus genotypes 1 to 6: implications for cross-genotype activity (English)

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20 March 2020

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4

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author name string

Chunfu Wang

1

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20 March 2020

Lingling Jia

2

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20 March 2020

Donald R O'Boyle

3

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20 March 2020

Karen Rigat

5

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20 March 2020

Lourdes Valera

6

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20 March 2020

Peter Nower

7

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20 March 2020

Xin Huang

8

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20 March 2020

Bernadette Kienzle

9

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20 March 2020

Susan Roberts

10

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20 March 2020

Min Gao

11

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20 March 2020

Robert A Fridell

12

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20 March 2020

language of work or name

English

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publication date

16 June 2014

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Antimicrobial Agents and Chemotherapy

20 March 2020

published in

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20 March 2020

volume

58

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issue

9

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20 March 2020

page(s)

5155-5163

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Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA.

20 March 2020

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29 May 2018

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29 May 2018

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29 May 2018

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Combination treatment with hepatitis C virus protease and NS5A inhibitors is effective against recombinant genotype 1a, 2a, and 3a viruses

29 May 2018

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In vitro activity of daclatasvir on hepatitis C virus genotype 3 NS5A.

29 May 2018

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MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants

29 May 2018

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Preliminary study of two antiviral agents for hepatitis C genotype 1.

29 May 2018

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Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5A replication complex inhibitor, BMS-790052.

29 May 2018

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Hepatitis C virus RNA elimination and development of resistance in replicon cells treated with BMS-790052

29 May 2018

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In vitro activity of BMS-790052 on hepatitis C virus genotype 4 NS5A.

29 May 2018

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Distinct functions of NS5A in hepatitis C virus RNA replication uncovered by studies with the NS5A inhibitor BMS-790052

29 May 2018

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Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: insights into compound modes of action

29 May 2018

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Recombinant HCV variants with NS5A from genotypes 1-7 have different sensitivities to an NS5A inhibitor but not interferon-α.

29 May 2018

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A perspective on modelling hepatitis C virus infection

29 May 2018

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Resistance analysis of the hepatitis C virus NS5A inhibitor BMS-790052 in an in vitro replicon system

29 May 2018

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Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

29 May 2018

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Effect of Ribavirin on the Mutation Rate and Spectrum of Hepatitis C Virus In Vivo

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29 May 2018

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29 May 2018

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Daclatasvir for previously untreated chronic hepatitis C genotype-1 infection: a randomised, parallel-group, double-blind, placebo-controlled, dose-finding, phase 2a trial

29 May 2018

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17 August 2018

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17 August 2018

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17 August 2018

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17 August 2018

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17 August 2018

Identifiers

DOI

10.1128/AAC.02788-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24936600%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

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20 March 2020

PubMed publication ID

24936600

1 reference