Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity. (Q42119017)

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scientific article published on 7 March 2012

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English	Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity.	scientific article published on 7 March 2012

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25 January 2020

Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity (English)

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Martin Holzenberger

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Zvezdana Mladenovic

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25 January 2020

Colette Salvat

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Emilie Pecchi

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Francis Berenbaum

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Marjolaine Gosset

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7 March 2012

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9

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Journal of Biological Chemistry

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15100-15108

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25 January 2020

Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes

1 reference

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29 May 2018

Expression and function of the insulin receptor in normal and osteoarthritic human chondrocytes: modulation of anabolic gene expression, glucose transport and GLUT-1 content by insulin.

1 reference

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C-28/I2 and T/C-28a2 chondrocytes as well as human primary articular chondrocytes express sex hormone and insulin receptors--Useful cells in study of cartilage metabolism

1 reference

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Visfatin-induced lipid raft redox signaling platforms and dysfunction in glomerular endothelial cells

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29 May 2018

Nampt/PBEF/visfatin and cancer

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29 May 2018

Visfatin: a potential therapeutic target for rheumatoid arthritis

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Visfatin regulates insulin secretion, insulin receptor signalling and mRNA expression of diabetes-related genes in mouse pancreatic beta-cells

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Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways

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29 May 2018

Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity

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Critical role of PBEF expression in pulmonary cell inflammation and permeability

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29 May 2018

Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD

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29 May 2018

Pre-B cell colony-enhancing factor (PBEF)/visfatin: a novel mediator of innate immunity

1 reference

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29 May 2018

Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

1 reference

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29 May 2018

The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation

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29 May 2018

Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization

1 reference

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29 May 2018

Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866

1 reference

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Osteoarthritis: pathobiology-targets and ways for therapeutic intervention

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29 May 2018

A review of the effects of insulin-like growth factor and platelet derived growth factor on in vivo cartilage healing and repair

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Membrane rafts segregate pro- from anti-apoptotic insulin-like growth factor-I receptor signaling in colon carcinoma cells stimulated by members of the tumor necrosis factor superfamily

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Influence of the crosstalk between growth hormone and insulin signalling on the modulation of insulin sensitivity

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Hormonal regulation of the novel adipocytokine visfatin in 3T3-L1 adipocytes

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Interleukin-6 is a negative regulator of visfatin gene expression in 3T3-L1 adipocytes

1 reference

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29 May 2018

RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340217

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Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways

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Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis

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29 May 2018

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

1 reference

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29 May 2018

Distinct and overlapping functions of insulin and IGF-I receptors

1 reference

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Posttranscriptional effect of insulin-like growth factor-I on interleukin-1beta-induced type II-secreted phospholipase A2 gene expression in rabbit articular chondrocytes

1 reference

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Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

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29 May 2018

Increased insulin-like growth factor 1 production by human osteoarthritic chondrocytes is not dependent on growth hormone action

1 reference

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Catalysis of serine and tyrosine autophosphorylation by the human insulin receptor

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29 May 2018

Overexpression of visfatin/PBEF/Nampt alters whole-body insulin sensitivity and lipid profile in rats

1 reference

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Impact of 3D-culture on the expression of differentiation markers and hormone receptors in growth plate chondrocytes as compared to articular chondrocytes.

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Primary culture and phenotyping of murine chondrocytes.

1 reference

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17 August 2018

Crucial role of visfatin/pre-B cell colony-enhancing factor in matrix degradation and prostaglandin E2 synthesis in chondrocytes: possible influence on osteoarthritis.

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Visfatin, an adipocytokine with proinflammatory and immunomodulating properties.

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Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.

1 reference

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17 August 2018

Retraction: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340217

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like effects of visfatin on human osteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.350215

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22399297%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22399297%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22399297%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

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