ATP independent type IB topoisomerase of Leishmania donovani is stimulated by ATP: an insight into the functional mechanism. (Q42125922)

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18 January 2020

title

ATP independent type IB topoisomerase of Leishmania donovani is stimulated by ATP: an insight into the functional mechanism (English)

1 reference

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DNA topoisomerase type IB small subunit

18 January 2020

main subject

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DNA topoisomerase type IB small subunit, putative

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DNA topoisomerase IB, large subunit

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Leishmania donovani

object named as

Leishmania donovani

1 reference

1

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18 January 2020

Alessandro Desideri

6

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18 January 2020

author name string

Agneyo Ganguly

2

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18 January 2020

Amit Roy

3

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18 January 2020

Somdeb Bosedasgupta

4

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18 January 2020

Ilda D'Annessa

5

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18 January 2020

Hemanta K Majumder

7

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18 January 2020

publication date

23 December 2010

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18 January 2020

published in

Nucleic Acids Research

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18 January 2020

volume

39

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18 January 2020

issue

8

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18 January 2020

page(s)

3295-3309

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Creative Commons Attribution-NonCommercial 2.5 Generic

18 January 2020

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Effects of magnesium and related divalent metal ions in topoisomerase structure and function.

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'LeishMan' topoisomerase I: an ideal chimera for unraveling the role of the small subunit of unusual bi-subunit topoisomerase I from Leishmania donovani

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Impact of the C-terminal domain of topoisomerase IIalpha on the DNA cleavage activity of the human enzyme

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The role of histidine 632 in catalysis by human topoisomerase I.

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29 May 2018

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Characterization of a Leishmania donovani gene encoding a protein that closely resembles a type IB topoisomerase

29 May 2018

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Vaccinia virus DNA topoisomerase: a model eukaryotic type IB enzyme

29 May 2018

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The C-terminal domain but not the tyrosine 723 of human DNA topoisomerase I active site contributes to kinase activity

29 May 2018

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A model for the mechanism of human topoisomerase I

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Biochemical and biophysical analyses of recombinant forms of human topoisomerase I

29 May 2018

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Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions

29 May 2018

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Effects of ATP and inhibitory factors on the activity of vaccinia virus type I topoisomerase

29 May 2018

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Inhibition of HeLa cell DNA topoisomerase I by ATP and phosphate

29 May 2018

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Characterization of vaccinia virus DNA topoisomerase I expressed in Escherichia coli

29 May 2018

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29 May 2018

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The large subunit of Leishmania topoisomerase I functions as the 'molecular steer' in type IB topoisomerase

29 May 2018

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Amino acids 39-456 of the large subunit and 210-262 of the small subunit constitute the minimal functionally interacting fragments of the unusual heterodimeric topoisomerase IB of Leishmania

17 August 2018

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An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3,3'-di-indolylmethane, a novel DNA topoisomerase I poison with a strong binding affinity to the enzyme.

17 August 2018

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The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA.

17 August 2018

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N-terminal region of the large subunit of Leishmania donovani bisubunit topoisomerase I is involved in DNA relaxation and interaction with the smaller subunit

17 August 2018

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Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani.

17 August 2018

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Characterization of the nucleotide binding properties of SV40 T antigen using fluorescent 3'(2')-O-(2,4,6-trinitrophenyl)adenine nucleotide analogues

17 August 2018

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17 August 2018

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17 August 2018

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12 December 2020

Mechanism of ATP inhibition of mammalian type I DNA topoisomerase: DNA binding, cleavage, and rejoining are insensitive to ATP

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Binding of ATP to human DNA topoisomerase I resulting in an alteration of the conformation of the enzyme

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12 December 2020

Leishmania donovani bisubunit topoisomerase I gene fusion leads to an active enzyme with conserved type IB enzyme function

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKQ1284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186185%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21186185%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

21186185

1 reference