Hypoxia down-regulates sFlt-1 (sVEGFR-1) expression in human microvascular endothelial cells by a mechanism involving mRNA alternative processing. (Q42155801)

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English	Hypoxia down-regulates sFlt-1 (sVEGFR-1) expression in human microvascular endothelial cells by a mechanism involving mRNA alternative processing.	scientific article

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Hypoxia down-regulates sFlt-1 (sVEGFR-1) expression in human microvascular endothelial cells by a mechanism involving mRNA alternative processing (English)

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Takayuki Ikeda

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Li Sun

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Yasuhito Ishigaki

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Yasuo Yoshitomi

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Yoshino Yoshitake

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Hideto Yonekura

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1 June 2011

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Biochemical Journal

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399-407

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25 July 2019

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A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use.

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Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

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Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

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10.1042/BJ20101490

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24 January 2020

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