Proximal tubule specific knockout of the Na⁺/H⁺ exchanger NHE3: effects on bicarbonate absorption and ammonium excretion (Q42155895)

17 October 2017

Proximal tubule specific knockout of the Na⁺/H⁺ exchanger NHE3: effects on bicarbonate absorption and ammonium excretion (English)

1 reference

17 October 2017

Hong C Li

1

1 reference

17 October 2017

Zhaopeng Du

2

1 reference

17 October 2017

Sharon Barone

3

1 reference

17 October 2017

Isabelle Rubera

4

1 reference

17 October 2017

Alicia A McDonough

5

1 reference

17 October 2017

Michel Tauc

6

1 reference

17 October 2017

Kamyar Zahedi

7

1 reference

17 October 2017

Tong Wang

8

1 reference

17 October 2017

Manoocher Soleimani

9

1 reference

17 October 2017

19 March 2013

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Journal of Molecular Medicine

17 October 2017

1 reference

17 October 2017

91

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17 October 2017

951-963

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17 October 2017

8

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Creative Commons Attribution-NonCommercial 2.0 Generic

17 October 2017

start time

19 March 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3730089/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1007/s00109-013-1015-3

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cites work

Double knockout of pendrin and Na-Cl cotransporter (NCC) causes severe salt wasting, volume depletion, and renal failure

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Insulin resistance, obesity, hypertension, and renal sodium transport

29 May 2018

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High sodium intake increases HCO(3)- absorption in medullary thick ascending limb through adaptations in basolateral and apical Na+/H+ exchangers

29 May 2018

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Role of NH3 and NH4+ transporters in renal acid-base transport

29 May 2018

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Vasopressin V2 receptors, ENaC, and sodium reabsorption: a risk factor for hypertension?

29 May 2018

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Effect of metabolic acidosis on neonatal proximal tubule acidification

29 May 2018

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The regulation of proximal tubular salt transport in hypertension: an update

29 May 2018

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Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension

29 May 2018

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Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice

29 May 2018

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Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance

29 May 2018

1 reference

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Na+/H+ Exchangers in Renal Regulation of Acid-Base Balance

29 May 2018

1 reference

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Recent concepts concerning the renal handling of NH3/NH4+.

29 May 2018

1 reference

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Na+/H+ exchangers and the regulation of volume

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Missense mutations in Na+:HCO3- cotransporter NBC1 show abnormal trafficking in polarized kidney cells: a basis of proximal renal tubular acidosis.

29 May 2018

1 reference

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Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis

29 May 2018

1 reference

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Ion exchangers mediating NaCl transport in the renal proximal tubule

29 May 2018

1 reference

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Bicarbonate transport along the loop of Henle: molecular mechanisms and regulation.

29 May 2018

1 reference

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Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Coordinated down-regulation of NBC-1 and NHE-3 in sodium and bicarbonate loading

29 May 2018

1 reference

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Endothelin-1/endothelin-B receptor-mediated increases in NHE3 activity in chronic metabolic acidosis

29 May 2018

1 reference

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Immunoelectron microscopic localization of the electrogenic Na/HCO(3) cotransporter in rat and ambystoma kidney.

29 May 2018

1 reference

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Ontogeny of Na+/H+ antiporter activity in rat proximal convoluted tubules

29 May 2018

1 reference

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Uncompensated polyuria in a mouse model of Bartter's syndrome

29 May 2018

1 reference

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Hyposmolality stimulates apical membrane Na(+)/H(+) exchange and HCO(3)(-) absorption in renal thick ascending limb

29 May 2018

1 reference

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Micropuncture analysis of single-nephron function in NHE3-deficient mice

29 May 2018

1 reference

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Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger.

29 May 2018

1 reference

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Functional and molecular characterization of NHE3 expression during ontogeny in rat jejunal epithelium

29 May 2018

1 reference

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The Na+/H+ exchange isoform NHE3 regulates basal canine ileal Na+ absorption in vivo

29 May 2018

1 reference

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Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

NHE3: a Na+/H+ exchanger isoform of renal brush border

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Ammonia production by individual segments of the rat nephron

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Control of fluid absorption in the renal proximal tubule

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Spontaneous luminal disequilibrium pH in S3 proximal tubules. Role in ammonia and bicarbonate transport

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Luminal secretion of ammonia in the mouse proximal tubule perfused in vitro

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Effect of bath and luminal potassium concentration on ammonia production and secretion by mouse proximal tubules perfused in vitro

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Slc26a11, a chloride transporter, localizes with the vacuolar H(+)-ATPase of A-intercalated cells of the kidney.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Mouse model of type II Bartter's syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Role of angiotensin II in the enhancement of ammonia production and secretion by the proximal tubule in metabolic acidosis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Axial flow modulates proximal tubule NHE3 and H-ATPase activities by changing microvillus bending moments

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Blood pressure maintenance in NHE3-deficient mice with transgenic expression of NHE3 in small intestine

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Ammonia production and secretion by S3 proximal tubule segments from acidotic mice: role of ANG II.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Specific Cre/Lox recombination in the mouse proximal tubule

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Downregulation of renal AQP2 water channel and NKCC2 in mice lacking the apical Na+‐H+ exchanger NHE3

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Renal function in NHE3-deficient mice with transgenic rescue of small intestinal absorptive defect

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3730089

NH4+ as a substrate for apical and basolateral Na(+)-H+ exchangers of thick ascending limbs of rat kidney: evidence from isolated membranes

17 August 2018

1 reference

12 December 2020

Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice

1 reference

12 December 2020

Respective roles of H-ATPase and H-K-ATPase in ion transport in the kidney

1 reference

12 December 2020

Role of NHE3 in mediating renal brush border Na+-H+ exchange. Adaptation to metabolic acidosis

1 reference

12 December 2020

NHE2 and NHE3 are human and rabbit intestinal brush-border proteins

1 reference

12 December 2020

Aldosterone stimulates intestinal Na+ absorption in rats by increasing NHE3 expression of the proximal colon

1 reference

12 December 2020

Microelectrode characterization of the basolateral membrane of rabbit S3 proximal tubule

1 reference

12 December 2020

Chronic metabolic acidosis increases NHE3 protein abundance in rat kidney

1 reference

12 December 2020

Na+/H+ exchanger subtypes in the renal tubule: function and regulation in physiology and disease

1 reference

12 December 2020

Regulation of thick ascending limb ion transporter abundance in response to altered acid/base intake

1 reference

12 December 2020

Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics

1 reference

12 December 2020

Interaction of NH4+ and Li+ with the renal microvillus membrane Na+-H+ exchanger

1 reference

12 December 2020

10.1007/S00109-013-1015-3

Identifiers

DOI

1 reference

17 October 2017

1 reference

17 October 2017

1 reference