Native conformations of human complement components C3 and C4 show different dependencies on thioester formation (Q42159443)

17 October 2017

Native conformations of human complement components C3 and C4 show different dependencies on thioester formation (English)

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17 October 2017

L Isaac

1

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17 October 2017

D Aivazian

2

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17 October 2017

A Taniguchi-Sidle

3

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17 October 2017

R O Ebanks

4

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17 October 2017

C S Farah

5

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17 October 2017

M P Florido

6

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17 October 2017

M K Pangburn

7

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17 October 2017

D E Isenman

8

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17 October 2017

language of work or name

English

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publication date

1 February 1998

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17 October 2017

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17 October 2017

329 ( Pt 3)

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17 October 2017

705-712

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Amino acid sequence of hen ovomacroglobulin (ovostatin) deduced from cloned cDNA.

17 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

alpha 2-Macroglobulin, complement, and biologic defense: antigens, growth factors, microbial proteases, and receptor ligation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Thiol ester role in correct folding and conformation of human alpha 2-macroglobulin. Properties of recombinant C949S variant

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Synthesis of a Cys949Tyr alpha 2-macroglobulin thiol ester mutant: co-transfection with wild-type alpha 2-macroglobulin in an episomal expression system.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Ligand binding, conformational change and plasma elimination of human, mouse and rat α-macroglobulin proteinase inhibitors

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Structural requirements for thioester bond formation in human complement component C3. Reassessment of the role of thioester bond integrity on the conformation of C3

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Third component of human complement: purification from plasma and physicochemical characterization

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Functional studies on the secreted form of human C4 (C4s), two incompletely processed two-subunit C4 molecules (beta - alpha + gamma and beta + alpha - gamma), and pro-C4

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Nucleophilic modification of human complement protein C3: correlation of conformational changes with acquisition of C3b-like functional properties

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Fourth component of human complement: studies of an amine-sensitive site comprised of a thiol component.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Kinetics of the conformational alterations associated with nucleophilic modification of .alpha.2-macrobglobulin

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

Physical properties of human alpha 2-macroglobulin following reaction with methylamine and trypsin.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1219096

A single arginine to tryptophan interchange at beta-chain residue 458 of human complement component C4 accounts for the defect in classical pathway C5 convertase activity of allotype C4A6. Implications for the location of a C5 binding site in C4

17 August 2018

1 reference

12 December 2020

Third component of human complement: structural requirements for its function

1 reference

12 December 2020

Treatment of human complement components C4 and C3 with amines or chaotropic ions. Evidence of a functional and structural change that provides uncleaved C4 and C3 with properties of their soluble activated froms, C4b and C3b

1 reference

12 December 2020

Conformational and functional changes in the fourth component of human complement produced by nucleophilic modification and by proteolysis with C1s-

1 reference

12 December 2020

From CoA to complement: thioesters as the spring in the molecular mouse trap

1 reference

12 December 2020

Effect of protease binding by .alpha.2-macroglobulin on intrinsic fluorescence

1 reference

12 December 2020

Conformational changes induced in human .alpha.2-macroglobulin by protease and nucleophilic modification

1 reference

12 December 2020

Identification of “embryonin” as bovine alpha 2-macroglobulin

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12 December 2020

Intrinsic fluorescence analyses of structure-function relationships during alpha 2-macroglobulin-protease reactions

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12 December 2020

The methylamine reactive site and protease inhibition in alpha 2-macroglobulin

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12 December 2020

Autolytic fragmentation of complement components C3 and C4 and its relationship to covalent binding activity

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12 December 2020

Comparison of the binding of chicken α-macroglobulin and ovomacroglobulin to the mammalian α2-macroglobulin receptor

1 reference

12 December 2020

A fluorimetric assay for native C3. The hemolytically active form of the third component of human complement

1 reference

12 December 2020

Mutagenesis of the Arg-Gly-Asp triplet in human complement component C3 does not abolish binding of iC3b to the leukocyte integrin complement receptor type III (CR3, CD11b/CD18)

1 reference

12 December 2020

Spontaneous reformation of the intramolecular thioester in complement protein C3 and low temperature capture of a conformational intermediate capable of reformation

1 reference

12 December 2020

Spontaneous thioester bond formation in alpha 2-macroglobulin, C3 and C4

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12 December 2020

Identifiers

DOI

10.1042/BJ3290705

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17 October 2017

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17 October 2017

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