The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice (Q42171425)

17 October 2017

The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice (English)

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17 October 2017

3

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17 October 2017

Carmine M Pariante

8

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Stafford Lightman

object named as

Stafford Lightman

6

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author name string

Joyce L W Yau

1

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17 October 2017

June Noble

2

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17 October 2017

Robert Kerwin

4

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17 October 2017

Phillip E Morgan

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17 October 2017

Jonathan R Seckl

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17 October 2017

language of work or name

English

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publication date

14 March 2007

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17 October 2017

Neuropsychopharmacology

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17 October 2017

32

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17 October 2017

12

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17 October 2017

2520-2529

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1301389

17 October 2017

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cites work

Two cases involving clomipramine intoxication

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Macroscopic, microscopic and biochemical characterisation of spontaneous colitis in a transgenic mouse, deficient in the multiple drug resistance 1a gene

21 January 2018

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7 January 2021

Mood stabilizers inhibit glucocorticoid receptor function in LMCAT cells

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7 January 2021

Antipsychotic drugs inhibit the human corticotropin-releasing-hormone gene promoter activity in neuro-2A cells-an involvement of protein kinases

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7 January 2021

Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner

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7 January 2021

Clinical and biochemical results of a fatal case of desipramine intoxication

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7 January 2021

Brain pharmacokinetics and tissue distribution in vivo of fluvoxamine and fluoxetine by fluorine magnetic resonance spectroscopy

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7 January 2021

Antidepressant drugs inhibit glucocorticoid receptor-mediated gene transcription - a possible mechanism

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7 January 2021

Regulation of the human corticotropin-releasing-hormone gene promoter activity by antidepressant drugs in Neuro-2A and AtT-20 cells

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7 January 2021

Corticosteroids in brain tissue

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7 January 2021

Clinical and biological effects of mifepristone treatment for psychotic depression

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7 January 2021

Brain concentrations of tricyclic antidepressants: single-dose kinetics and relationship to plasma concentrations in chronically dosed rats.

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7 January 2021

P-glycoprotein reduces the ability of amitriptyline metabolites to cross the blood brain barrier in mice after a 10-day administration of amitriptyline

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7 January 2021

Differential effects of antidepressants on glucocorticoid receptors in human primary blood cells and human monocytic U-937 cells

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7 January 2021

Antidepressants differentially influence the transcriptional activity of the glucocorticoid receptor in vitro

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7 January 2021

Expression of mRNAs of multidrug resistance proteins (Mrps) in cultured rat astrocytes, oligodendrocytes, microglial cells and neurones.

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7 January 2021

The corticosteroid receptor hypothesis of depression

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7 January 2021

Different responses to dexamethasone and prednisolone in the same depressed patients.

1 reference

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7 January 2021

The role of the efflux transporter P-glycoprotein in brain penetration of prednisolone

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7 January 2021

Pharmacological and nonpharmacological factors influencing hypothalamic-pituitary-adrenocortical axis reactivity in acutely depressed psychiatric in-patients, measured by the Dex-CRH test

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7 January 2021

Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture

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7 January 2021

Negative Immunoregulatory Effects of Antidepressants Inhibition of Interferon-γ and Stimulation of Interleukin-10 Secretion

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7 January 2021

Early postnatal handling alters glucocorticoid receptor concentrations in selected brain regions.

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7 January 2021

Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

The phosphodiesterase type 4 inhibitor, rolipram, enhances glucocorticoid receptor function

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Partial glucocorticoid agonist-like effects of imipramine on hypothalamic-pituitary-adrenocortical activity, thymus weight, and hippocampal glucocorticoid receptors in male C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Reduced glucocorticoid receptors: consequence or cause of depression?

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7 January 2021

Treatment of mood disorders

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7 January 2021

Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones.

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7 January 2021

Glucocorticoid receptor function in vitro in patients with major depression

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7 January 2021

The glucocorticoid receptor: part of the solution or part of the problem?

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7 January 2021

The antidepressant clomipramine regulates cortisol intracellular concentrations and glucocorticoid receptor expression in fibroblasts and rat primary neurones

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Antidepressant fluoxetine enhances glucocorticoid receptor function in vitro by modulating membrane steroid transporters

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Four days of citalopram increase suppression of cortisol secretion by prednisolone in healthy volunteers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Steroid-independent translocation of the glucocorticoid receptor by the antidepressant desipramine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Do antidepressants regulate how cortisol affects the brain?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Hormonal regulation of type II glucocorticoid receptor messenger ribonucleic acid in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Antidepressant and other centrally acting drugs regulate glucocorticoid receptor messenger RNA levels in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Antidepressants regulate glucocorticoid receptor messenger RNA concentrations in primary neuronal cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Differential regulation by dexamethasone of glucocorticoid receptor messenger RNA concentrations in neuronal cultures derived from fetal rat hypothalamus and cerebral cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Norepinephrine-independent regulation of GRII mRNA in vivo by a tricyclic antidepressant.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Down-regulation of neural corticosterone receptors by corticosterone and dexamethasone.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Antidepressants increase glucocorticoid and mineralocorticoid receptor mRNA expression in rat hippocampus in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

A Fatal Case of Poisoning with Amitriptyline

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Anti-psychotic drugs reverse multidrug resistance of tumor cell lines and human AML cells ex-vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

abcb1ab P-glycoprotein is involved in the uptake of citalopram and trimipramine into the brain of mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Penetration of endogenous steroid hormones corticosterone, cortisol, aldosterone and progesterone into the brain is enhanced in mice deficient for both mdr1a and mdr1b P-glycoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Inhibition of Jun N-terminal kinase (JNK) enhances glucocorticoid receptor-mediated function in mouse hippocampal HT22 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Effects of antidepressants on the brain/plasma distribution of corticosterone.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Inhibition of P-glycoprotein function by several antidepressants may not contribute to clinical efficacy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Inhibition of P-glycoprotein by newer antidepressants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Prenatal glucocorticoid programming of brain corticosteroid receptors and corticotrophin-releasing hormone: possible implications for behaviour

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Short-term administration of fluoxetine and venlafaxine decreases corticosteroid receptor mRNA expression in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Site-specific regulation of corticosteroid and serotonin receptor subtype gene expression in the rat hippocampus following 3,4-methylenedioxymethamphetamine: role of corticosterone and serotonin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Effect of sertraline on glucocorticoid sensitivity of mononuclear leukocytes in post-traumatic stress disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Effect of topiramate on glucocorticoid receptor mediated action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Mineralocorticoid receptor function in major depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301389

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1301389

1 reference

Dimensions Publication ID

17 October 2017

1020910599

0 references

Fatcat ID

release_tb2l57ypjre43deed4xuzwvo64

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tb2l57ypjre43deed4xuzwvo64

24 November 2022

mapped directly with Wikidata item

1 reference