Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT. (Q42179793)

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scientific article published on May 2007

Language	Label	Description	Also known as
English	Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.	scientific article published on May 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT. (English)

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Zandrea Ambrose

object named as

Zandrea Ambrose

3

0 references

Gilda Tachedjian

object named as

Gilda Tachedjian

7

0 references

Noureddine Hamamouch

5

object named as

Noureddine Hamamouch

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Nicolas Sluis-Cremer

8

object named as

Nicolas Sluis-Cremer

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

author name string

Dwight V Nissley

1

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Jessica Radzio

2

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Chih-Wei Sheen

4

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Katie L Moore

6

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

language of work or name

0 references

publication date

1 May 2007

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Biochemical Journal

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Europe PubMed Central

PMC publication ID

18 October 2017

404

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

1

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

151-157

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Blinded, multicenter comparison of methods to detect a drug-resistant mutant of human immunodeficiency virus type 1 at low frequency

1 reference

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Antiviral therapy targeting viral polymerase

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Sensitive phenotypic detection of minor drug-resistant human immunodeficiency virus type 1 reverse transcriptase variants

1 reference

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Anti-human immunodeficiency virus type 1 activity of the nonnucleoside reverse transcriptase inhibitor GW678248 in combination with other antiretrovirals against clinical isolate viruses and in vitro selection for resistance

1 reference

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Antiviral activity of GW678248, a novel benzophenone nonnucleoside reverse transcriptase inhibitor

1 reference

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The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations

1 reference

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The role of Thr139 in the human immunodeficiency virus type 1 reverse transcriptase sensitivity to (+)-calanolide A.

1 reference

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1 reference

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Characterization of a subtype D human immunodeficiency virus type 1 isolate that was obtained from an untreated individual and that is highly resistant to nonnucleoside reverse transcriptase inhibitors

1 reference

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Reduced susceptibility of human immunodeficiency virus type 1 (HIV-1) from patients with primary HIV infection to nonnucleoside reverse transcriptase inhibitors is associated with variation at novel amino acid sites

1 reference

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Analysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase

1 reference

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Hybrid Ty1/HIV-1 elements used to detect inhibitors and monitor the activity of HIV-1 reverse transcriptase

1 reference

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Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro

1 reference

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A recombinant retroviral system for rapid in vivo analysis of human immunodeficiency virus type 1 susceptibility to reverse transcriptase inhibitors

1 reference

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Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C-->C181I)RT HIV-1 mutants

1 reference

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Factors contributing to the inhibition of HIV reverse transcriptase by chain-terminating nucleotides in vitro and in vivo

1 reference

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Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

1 reference

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The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection.

1 reference

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Dimerization of human immunodeficiency virus type 1 reverse transcriptase. A target for chemotherapeutic intervention.

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In vitro selection of mutations in human immunodeficiency virus type 1 reverse transcriptase that confer resistance to capravirine, a novel nonnucleoside reverse transcriptase inhibitor

1 reference

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Sensitive drug-resistance assays reveal long-term persistence of HIV-1 variants with the K103N nevirapine (NVP) resistance mutation in some women and infants after the administration of single-dose NVP: HIVNET 012.

1 reference

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17 August 2018

The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs

1 reference

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The amino acid Asn136 in HIV-1 reverse transcriptase (RT) maintains efficient association of both RT subunits and enables the rational design of novel RT inhibitors

1 reference

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The beta7-beta8 loop of the p51 subunit in the heterodimeric (p66/p51) human immunodeficiency virus type 1 reverse transcriptase is essential for the catalytic function of the p66 subunit

1 reference

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HIV reverse transcription in yeast

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Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138

1 reference

https://pubmed.ncbi.nlm.nih.gov/17286555

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mixed reconstitution of mutated subunits of HIV-1 reverse transcriptase coexpressed in Escherichia coli - two tags tie it up

1 reference

https://pubmed.ncbi.nlm.nih.gov/17286555

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17286555

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20061814

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

ResearchGate publication ID

0 references

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