Relationship between cytotoxicity, drug accumulation, DNA damage and repair of human ovarian cancer cells treated with doxorubicin: modulation by the tiapamil analog RO11-2933. (Q42192495)

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English	Relationship between cytotoxicity, drug accumulation, DNA damage and repair of human ovarian cancer cells treated with doxorubicin: modulation by the tiapamil analog RO11-2933.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

Relationship between cytotoxicity, drug accumulation, DNA damage and repair of human ovarian cancer cells treated with doxorubicin: modulation by the tiapamil analog RO11-2933. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

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author name string

M A Alaoui Jamali

1

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Europe PubMed Central

PubMed publication ID

18 October 2017

M B Yin

2

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Europe PubMed Central

PubMed publication ID

18 October 2017

A Mazzoni

3

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Europe PubMed Central

PubMed publication ID

18 October 2017

I Bankusli

4

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Europe PubMed Central

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18 October 2017

Y M Rustum

5

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PubMed publication ID

18 October 2017

publication date

1 January 1989

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Europe PubMed Central

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18 October 2017

Cancer Chemotherapy and Pharmacology

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Europe PubMed Central

PubMed publication ID

18 October 2017

25

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Europe PubMed Central

PubMed publication ID

18 October 2017

2

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Europe PubMed Central

PubMed publication ID

18 October 2017

77-83

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Europe PubMed Central

PubMed publication ID

18 October 2017

describes a project that uses

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Promotion of daunorubicin uptake and toxicity by the calcium antagonist tiapamil and its analogs.

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https://pubmed.ncbi.nlm.nih.gov/2598402

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Anthracycline antibiotic augmentation of microsomal electron transport and free radical formation

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https://pubmed.ncbi.nlm.nih.gov/2598402

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Stereochemistry of Intercalation: Interaction of Daunomycin with DNA

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Characterization of multidrug resistance in SEWA mouse tumor cells: increased glutathione transferase activity and reversal of resistance with verapamil

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https://pubmed.ncbi.nlm.nih.gov/2598402

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Multifactorial drug resistance in an adriamycin-resistant human small cell lung carcinoma cell line

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https://pubmed.ncbi.nlm.nih.gov/2598402

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X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers.

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Verapamil-mediated sensitization of doxorubicin-selected pleiotropic resistance in human sarcoma cells: selectivity for drugs which produce DNA scission.

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Relationship between DNA ploidy, glandular differentiation, and tumor spread in human prostate cancer

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https://pubmed.ncbi.nlm.nih.gov/2598402

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Phase I and pharmacological studies of adriamycin administered intraperitoneally to patients with ovarian cancer

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https://pubmed.ncbi.nlm.nih.gov/2598402

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Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Molecular pharmacology of the haloethyl nitrosoureas: formation of 6-hydroxyethylguanine in DNA treated with BCNU (N,N1-bis[2-chloroethyl]-N-nitrosourea)

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Protein measurement with the Folin phenol reagent

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https://pubmed.ncbi.nlm.nih.gov/2598402

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Increased mortality with cardiotoxic doses of Adriamycin after verapamil pretreatment despite prevention of myocardial calcium accumulation

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Synthesis of adriamycin-coupled polyglutaraldehyde microspheres and evaluation of their cytostatic activity

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https://pubmed.ncbi.nlm.nih.gov/2598402

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based on heuristic

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Reversal of Adriamycin Resistance by Verapamil in Human Ovarian Cancer

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Ovarian cancer treatment: progress or paralysis?

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Reversal of acquired resistance to doxorubicin in P388 murine leukemia cells by perhexiline maleate

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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The effects of verapamil and a tiapamil analogue, DMDP, on adriamycin-induced cytotoxicity in P388 adriamycin-resistant and -sensitive leukemia in vitro and in vivo

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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The anticancer agent adriamycin can be actively cytotoxic without entering cells

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Adriamycin-induced changes in the surface membrane of sarcoma 180 ascites cells

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Fluorometric determination of serum levels and urinary excretion of daunomycin (NSC-82151) in mice and rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Adriamycin accumulation and metabolism in adriamycin-sensitive and -resistant human ovarian cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Alterations in cell surface membranes in Chinese hamster lung cell resistant to adriamycin.

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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O6-Methylguanine-DNA methyltransferase of human lymphoid cells: structural and kinetic properties and absence in repair-deficient cells

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Multiple mechanisms of resistance to cis-diamminedichloroplatinum(II) in murine leukemia L1210 cells.

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Effect of verapamil and other agents on the distribution of anthracyclines and on reversal of drug resistance.

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Verapamil Restoration of Daunorubicin Responsiveness in Daunorubicin-resistant Ehrlich Ascites Carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

based on heuristic

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Uptake and retention of adriamycin and daunorubicin by sensitive and anthracycline-resistant sublines of P388 leukemia

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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The anthracycline antineoplastic drugs

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https://pubmed.ncbi.nlm.nih.gov/2598402

12 December 2020

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Identifiers

10.1007/BF00692343

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

Dimensions Publication ID

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

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