Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial (Q42199381)

18 October 2017

title

Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial (English)

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18 October 2017

main subject

phase I clinical trial

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17

Theodore C Pierson

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John R Mascola

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2

Kimberly A Dowd

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Gary J Nabel

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Barney S Graham

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Julie E Ledgerwood

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Mary E Enama

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Richard A Koup

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Richard M Schwartz

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Uzma N Sarwar

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Galina Yamshchikov

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3

Floreliz H Mendoza

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5

Sandra Sitar

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1

Lee-Jah Chang

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Wataru Akahata

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Sarah H Plummer

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Jamie G Saunders

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Zonghui Hu

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9

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Robert T Bailer

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11

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VRC 311 Study Team

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20

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language of work or name

English

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publication date

14 August 2014

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18 October 2017

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volume

384

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issue

9959

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page(s)

2046-2052

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on focus list of Wikimedia project

18 October 2017

ScienceSource

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Comparative role of Aedes albopictus and Aedes aegypti in the emergence of Dengue and Chikungunya in central Africa

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Infection with chikungunya virus in Italy: an outbreak in a temperate region

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Persistent chronic inflammation and infection by Chikungunya arthritogenic alphavirus in spite of a robust host immune response

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Detection of viral ribonucleic acid and histologic analysis of inflamed synovium in Ross River virus infection

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7 January 2021

Persistent arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony-stimulating factor

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Atypical manifestations of chikungunya infection

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Chikungunya and the nervous system: what we do and do not know

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Neurological complications of Chikungunya virus infection

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7 January 2021

Longitudinal analysis of the human antibody response to Chikungunya virus infection: implications for serodiagnosis and vaccine development

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7 January 2021

Early appearance of neutralizing immunoglobulin G3 antibodies is associated with chikungunya virus clearance and long-term clinical protection

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7 January 2021

Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response

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7 January 2021

Phase II safety and immunogenicity study of live chikungunya virus vaccine TSI-GSD-218.

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7 January 2021

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7 January 2021

Assessment of immunogenic potential of Vero adapted formalin inactivated vaccine derived from novel ECSA genotype of Chikungunya virus

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7 January 2021

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7 January 2021

Effective chikungunya virus-like particle vaccine produced in insect cells

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7 January 2021

Chikungunya virus-like particles are more immunogenic in a lethal AG129 mouse model compared to glycoprotein E1 or E2 subunits

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7 January 2021

A novel poxvirus-based vaccine, MVA-CHIKV, is highly immunogenic and protects mice against chikungunya infection.

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A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus

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7 January 2021

Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice

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7 January 2021

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7 January 2021

Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus

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7 January 2021

Durable antibody responses following one dose of the bivalent human papillomavirus L1 virus-like particle vaccine in the Costa Rica Vaccine Trial

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7 January 2021

Prophylaxis and therapy for Chikungunya virus infection

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7 January 2021

10.1016/S0140-6736(14)61185-5

Identifiers

DOI

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18 October 2017

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