Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein. (Q42214633)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20622013%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20622013%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

0 references

3

1 reference

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7 February 2020

4

Rudolph E Tanzi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20622013%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Can Zhang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20622013%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Andrew Browne

series ordinal

2

1 reference

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7 February 2020

language of work or name

English

0 references

publication date

9 July 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20622013%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

7 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20622013%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

285

1 reference

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7 February 2020

issue

37

1 reference

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7 February 2020

page(s)

28472-28480

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20622013%20AND%20SRC:MED&resulttype=core&format=json

Familial Alzheimer's disease mutations in presenilin 1 do not alter levels of the secreted amyloid-beta protein precursor generated by beta-secretase cleavage

7 February 2020

cites work

1 reference

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Loss of function of ATXN1 increases amyloid beta-protein levels by potentiating beta-secretase processing of beta-amyloid precursor protein.

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Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.

26 October 2017

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Consumption of grape seed extract prevents amyloid-beta deposition and attenuates inflammation in brain of an Alzheimer's disease mouse

26 October 2017

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Development and validation of a high-density fluorescence polarization-based assay for the trypanosoma RNA triphosphatase TbCet1.

26 October 2017

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Inhibition of Alzheimer's amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo

26 October 2017

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Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease

26 October 2017

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An AICD-based functional screen to identify APP metabolism regulators.

26 October 2017

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Curcumin: the Indian solid gold

26 October 2017

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Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.

26 October 2017

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RNA interference silencing of the adaptor molecules ShcC and Fe65 differentially affect amyloid precursor protein processing and Abeta generation

26 October 2017

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Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis

26 October 2017

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Ubiquilin 1 modulates amyloid precursor protein trafficking and Abeta secretion

26 October 2017

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The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease

26 October 2017

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Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

26 October 2017

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RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.

26 October 2017

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Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

26 October 2017

1 reference

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Localization and functional analyses of the MLC1 protein involved in megalencephalic leukoencephalopathy with subcortical cysts

26 October 2017

1 reference

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Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects

26 October 2017

1 reference

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Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach.

26 October 2017

1 reference

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gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins

26 October 2017

1 reference

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Alzheimer's disease is a synaptic failure

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937872

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

26 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937872

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937872

Alzheimer's disease: genes, proteins, and therapy

26 October 2017

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Perspectives and progress in development of breast cancer chemopreventive drugs.

26 October 2017

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The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

26 October 2017

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Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease

26 October 2017

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Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

29 May 2018

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Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation

29 May 2018

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Therapeutic targeting of the alpha-secretase pathway to treat Alzheimer's disease.

17 August 2018

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HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation.

17 August 2018

1 reference

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Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937872

Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP).

17 August 2018

1 reference

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Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937872

Apolipoprotein E polymorphism and Alzheimer disease: The Indo-US Cross-National Dementia Study.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937872

17 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20622013

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20622013

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.133520

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20622013%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20622013%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference