Detection of native-state nonadditivity in double mutant cycles via hydrogen exchange (Q42217656)

18 October 2017

Detection of native-state nonadditivity in double mutant cycles via hydrogen exchange (English)

1 reference

18 October 2017

Joshua A Boyer

1

1 reference

18 October 2017

Cristina J Clay

2

1 reference

18 October 2017

K Scott Luce

3

1 reference

18 October 2017

Marshall H Edgell

4

1 reference

18 October 2017

Andrew L Lee

5

1 reference

18 October 2017

language of work or name

English

0 references

publication date

1 June 2010

1 reference

Journal of the American Chemical Society

18 October 2017

1 reference

18 October 2017

132

1 reference

18 October 2017

23

1 reference

18 October 2017

8010-8019

1 reference

NMR View: A computer program for the visualization and analysis of NMR data

18 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Mg2+-assisted catalysis by B. stearothermophilus TrpRS is promoted by allosteric effects

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Localized thermodynamic coupling between hydrogen bonding and microenvironment polarity substantially stabilizes proteins

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Long-range coupling in an allosteric receptor revealed by mutant cycle analysis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Analysing the origin of long-range interactions in proteins using lattice models

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Hydrophobic core mutations in CI2 globally perturb fast side-chain dynamics similarly without regard to position.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Principles underlying energetic coupling along an allosteric communication trajectory of a voltage-activated K+ channel

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Dynamic personalities of proteins

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Thermodynamic analysis shows conformational coupling and dynamics confer substrate specificity in fructose-1,6-bisphosphate aldolase

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

New insight into long-range nonadditivity within protein double-mutant cycles

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Networks for the allosteric control of protein kinases

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Dynamic coupling and allosteric behavior in a nonallosteric protein

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Protein folding pathways studied by pulsed- and native-state hydrogen exchange

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Hydrogen exchange mass spectrometry for the analysis of protein dynamics

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Protein folding: the stepwise assembly of foldon units

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Simultaneous determination of protein structure and dynamics.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Ligand-dependent dynamics and intramolecular signaling in a PDZ domain

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

High-precision, high-throughput stability determinations facilitated by robotics and a semiautomated titrating fluorometer.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Structural cooperativity in the SH3 domain studied by site-directed mutagenesis and amide hydrogen exchange.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the R(I)alpha subunit of protein kinase A.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Point mutations and sequence variability in proteins: redistributions of preexisting populations.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Two-state vs. multistate protein unfolding studied by optical melting and hydrogen exchange

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Hydrogen-exchange stabilities of RNase T1 and variants with buried and solvent-exposed Ala --> Gly mutations in the helix

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

The structural distribution of cooperative interactions in proteins: analysis of the native state ensemble

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Double-mutant cycles: a powerful tool for analyzing protein structure and function

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Global changes in amide hydrogen exchange rates for a protein antigen in complex with three different antibodies.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Primary structure effects on peptide group hydrogen exchange

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Protein folding intermediates: native-state hydrogen exchange

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Effects of site-specific amino acid modification on protein interactions and biological function

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Determination and analysis of urea and guanidine hydrochloride denaturation curves

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

The Energy Landscapes and Motions of Proteins

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Mutagenesis at a specific position in a DNA sequence

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Monitoring aromatic picosecond to nanosecond dynamics in proteins via 13C relaxation: expanding perturbation mapping of the rigidifying core mutation, V54A, in eglin c.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Backbone and side chain dynamics of mutant calmodulin-peptide complexes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Complex interactions at the helix-helix interface stabilize the glycophorin A transmembrane dimer

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Long-range dynamic effects of point mutations propagate through side chains in the serine protease inhibitor eglin c.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Direct demonstration of structural similarity between native and denatured eglin C.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Dissecting cooperative and additive binding energetics in the affinity maturation pathway of a protein-protein interface.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Protein hydrogen exchange mechanism: local fluctuations

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

pH corrections in chemical denaturant solutions.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Higher-order packing interactions in triple and quadruple mutants of staphylococcal nuclease

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Energetics of side chain packing in staphylococcal nuclease assessed by systematic double mutant cycles

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Hydrogen exchange of the tetramerization domain of the human tumour suppressor p53 probed by denaturants and temperature

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Guanidinium chloride induction of partial unfolding in amide proton exchange in RNase A.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059754

Evaluation of energetic and dynamic coupling networks in a PDZ domain protein

17 August 2018

1 reference

12 December 2020

Strategy for analysing the co-operativity of intramolecular interactions in peptides and proteins

1 reference

12 December 2020

Inverse coupling in leak and voltage-activated K+ channel gates underlies distinct roles in electrical signaling

1 reference

12 December 2020

Thermodynamic parameters from hydrogen exchange measurements

1 reference

12 December 2020

Patterns of nonadditivity between pairs of stability mutations in staphylococcal nuclease

1 reference

12 December 2020

Long-range, small magnitude nonadditivity of mutational effects in proteins

1 reference

12 December 2020

Protein conformational stabilities can be determined from hydrogen exchange rates

1 reference

12 December 2020

On the choice of reference mutant states in the application of the double-mutant cycle method

1 reference

12 December 2020

Protein stability parameters measured by hydrogen exchange

1 reference

12 December 2020

Substrate recognition reduces side-chain flexibility for conserved hydrophobic residues in human Pin1

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA1003922

1 reference

release_ncgbzy3nbzf7rafl534ep5jf6i

18 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ncgbzy3nbzf7rafl534ep5jf6i

24 November 2022

mapped directly with Wikidata item

1 reference

18 October 2017

PubMed publication ID

20481530

1 reference