Thrombomodulin improves early outcomes after intraportal islet transplantation (Q42220324)

18 October 2017

Thrombomodulin improves early outcomes after intraportal islet transplantation (English)

1 reference

18 October 2017

W Cui

1

1 reference

18 October 2017

J T Wilson

2

1 reference

18 October 2017

J Wen

3

1 reference

18 October 2017

J Angsana

4

1 reference

18 October 2017

Z Qu

5

1 reference

18 October 2017

C A Haller

6

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18 October 2017

E L Chaikof

7

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18 October 2017

language of work or name

English

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publication date

20 May 2009

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American Journal of Transplantation

18 October 2017

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18 October 2017

9

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18 October 2017

6

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18 October 2017

1308-1316

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Islet transplantation: where do we stand now?

18 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Engineering the proteolytic specificity of activated protein C improves its pharmacological properties

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Thrombin signalling and protease-activated receptors

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Regulation and functions of the protein C anticoagulant pathway

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Activation of intragraft endothelial and mononuclear cells during discordant xenograft rejection

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Transplantation of isolated pancreatic islets into the portal vein of diabetic rats

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Modulation of endothelial cell hemostatic properties by tumor necrosis factor

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

In vivo behavior of detergent-solubilized purified rabbit thrombomodulin on intravenous injection into rabbits

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Differential roles of Mac-1+ cells, and CD4+ and CD8+ T lymphocytes in primary nonfunction and classic rejection of islet allografts

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Effects of human soluble thrombomodulin on experimental glomerulonephritis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Antithrombotic effect of recombinant human soluble thrombomodulin on endotoxin-induced disseminated intravascular coagulation in rats.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Inhibition of platelet-dependent thrombus formation by human activated protein C in a primate model.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Immunobiology and therapeutic applications of protein c/protein s/thrombomodulin in human and experimental allotransplantation and xenotransplantation.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Reconstitution of CD39 in liposomes amplifies nucleoside triphosphate diphosphohydrolase activity and restores thromboregulatory properties.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Liver ischemia contributes to early islet failure following intraportal transplantation: benefits of liver ischemic-preconditioning

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Dose-response study of recombinant human soluble thrombomodulin (ART-123) in the prevention of venous thromboembolism after total hip replacement.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Activated protein C preserves functional islet mass after intraportal transplantation: a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

A membrane-mimetic barrier for islet encapsulation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Low-molecular weight dextran sulfate abrogates the instant blood-mediated inflammatory reaction induced by adult porcine islets both in vitro and in vivo

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood-mediated inflammatory reaction

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Capillary endothelial thrombomodulin expression and fibrin deposition in rats with continuous and bolus lipopolysaccharide administration.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Liposome disposition in vivo. III. Dose and vesicle-size effects

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759690

Reconstitution of rabbit thrombomodulin into phospholipid vesicles

17 August 2018

1 reference

12 December 2020

Prevention of primary nonfunction after porcine islet allotransplantation

1 reference

12 December 2020

Primary nonfunction of islet xenografts in rat recipients results from non-T-cell-mediated immune responses

1 reference

12 December 2020

Hepatic sinusoidal endothelium upregulates IL-1alpha, IFN-gamma, and iNOS in response to discordant xenogeneic islets in an in vitro model of xenoislet transplantation

1 reference

12 December 2020

Effects of recombinant human soluble thrombomodulin (rhs-TM) on a rat model of disseminated intravascular coagulation with decreased levels of plasma antithrombin III

1 reference

12 December 2020

Linkage between inflammation and coagulation: An update on the molecular basis of the crosstalk

1 reference

12 December 2020

Bacterial lipopolysaccharide decreases thrombomodulin expression in the sinusoidal endothelial cells of rats -- a possible mechanism of intrasinusoidal microthrombus formation and liver dysfunction

1 reference

12 December 2020

Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN-gamma, or phorbol ester

1 reference

12 December 2020

Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial

1 reference

12 December 2020

Prevention of bleeding after islet transplantation: lessons learned from a multivariate analysis of 132 cases at a single institution

1 reference

12 December 2020

Intravenous extended infusion of recombinant human soluble thrombomodulin prevented tissue factor-induced disseminated intravascular coagulation in rats

1 reference

12 December 2020

Antithrombotic effects of recombinant human soluble thrombomodulin (rhs-TM) on arteriovenous shunt thrombosis in rats

1 reference

12 December 2020

Human protein C inhibits selectin-mediated cell adhesion: role of unique fucosylated oligosaccharide

1 reference

12 December 2020

Blood coagulation equilibrium in rat liver microcirculation as evaluated by endothelial cell thrombomodulin and macrophage tissue factor

1 reference

12 December 2020

rhs-TM prevents ET-induced increase in pulmonary vascular permeability through protein C activation

1 reference

12 December 2020

Fatal disseminated intravascular coagulation after autologous islet transplantation

1 reference

12 December 2020

Deranged blood coagulation equilibrium as a factor of massive liver necrosis following endotoxin administration in partially hepatectomized rats

1 reference

12 December 2020

Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation

1 reference

12 December 2020

ENDOTOXIN CONTAMINATION MAY BE RESPONSIBLE FOR THE UNEXPLAINED FAILURE OF HUMAN PANCREATIC ISLET TRANSPLANTATION1

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12 December 2020

Neuroprotection by recombinant thrombomodulin

1 reference

12 December 2020

Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft

1 reference

12 December 2020

Recombinant thrombomodulin prevents endotoxin-induced lung injury in rats by inhibiting leukocyte activation

1 reference

12 December 2020

Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis

1 reference

12 December 2020

Primary nonfunction is not caused by accelerated rejection after pig-to-rat islet transplantation

1 reference

12 December 2020

A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice

1 reference

12 December 2020

Pharmacokinetics and safety of a novel recombinant soluble human thrombomodulin, ART-123, in healthy male volunteers

1 reference

12 December 2020

10.1111/J.1600-6143.2009.02652.X

Identifiers

DOI

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18 October 2017

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18 October 2017

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