Human antigen-specific CD4⁺ CD25⁺ CD134⁺ CD39⁺ T cells are enriched for regulatory T cells and comprise a substantial proportion of recall responses (Q42223144)

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scientific article published on 29 April 2014

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English	Human antigen-specific CD4⁺ CD25⁺ CD134⁺ CD39⁺ T cells are enriched for regulatory T cells and comprise a substantial proportion of recall responses	scientific article published on 29 April 2014

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scholarly article

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Europe PubMed Central

18 October 2017

Human antigen-specific CD4⁺ CD25⁺ CD134⁺ CD39⁺ T cells are enriched for regulatory T cells and comprise a substantial proportion of recall responses (English)

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18 October 2017

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Chansavath Phetsouphanh

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Cynthia Mee Ling Munier

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Nabila Seddiki

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Denise C Hsu

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Kai Brown

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Yin Xu

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Stephen J Kerr

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David A Cooper

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Sarah Pett

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Anthony D Kelleher

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Jintanat Ananworanich

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29 April 2014

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European Journal of Immunology

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1644-1661

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31 May 2020

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

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Regulatory T cells in HIV infection: who's suppressing what?

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

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Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

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Antigenic stimulation regulates the level of expression of interleukin 2 receptor on human T cells

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Increased plasma interleukin-7 level correlates with decreased CD127 and Increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection.

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

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Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.

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CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis

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Expression of CD39 by human peripheral blood CD4+ CD25+ T cells denotes a regulatory memory phenotype.

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CD39/adenosine pathway is involved in AIDS progression

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Expression of CD39 on FoxP3+ T regulatory cells correlates with progression of HBV infection.

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Functional regulatory T cells produced by inhibiting cyclic nucleotide phosphodiesterase type 3 prevent allograft rejection.

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Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells

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A novel assay for detection of hepatitis C virus-specific effector CD4(+) T cells via co-expression of CD25 and CD134.

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Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease.

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Interaction of Staphylococcus aureus toxin "superantigens" with human T cells

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FOXP3 promoter demethylation reveals the committed Treg population in humans.

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The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion.

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OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infection

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New insights on OX40 in the control of T cell immunity and immune tolerance in vivo

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OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection

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High sensitivity of CD4+CD25+ regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors

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21 January 2018

Ratios of effector to central memory antigen-specific CD4(+) T cells vary with antigen exposure in HIV+ patients.

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Varicella zoster-specific CD4+Foxp3+ T cells accumulate after cutaneous antigen challenge in humans

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Cytomegalovirus-specific regulatory and effector T cells share TCR clonality--possible relation to repetitive CMV infections.

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Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.

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DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells.

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Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes.

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Low-dose antigen promotes induction of FOXP3 in human CD4+ T cells

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Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity.

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Global mapping of H3K4me1 and H3K4me3 reveals the chromatin state-based cell type-specific gene regulation in human Treg cells

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The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

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Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expression

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High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell population

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Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

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Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

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Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

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Control of regulatory T cell development by the transcription factor Foxp3

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TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

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10.1002/EJI.201344102

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Europe PubMed Central

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31 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752698%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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