Effect of quinidine on the dextromethorphan O-demethylase activity of microsomal fractions from human liver (Q42229235)

19 October 2017

Effect of quinidine on the dextromethorphan O-demethylase activity of microsomal fractions from human liver (English)

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19 October 2017

Broly F

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19 October 2017

Libersa C

2

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19 October 2017

Lhermitte M

3

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19 October 2017

Bechtel P

4

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19 October 2017

Dupuis B

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19 October 2017

language of work or name

English

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publication date

1 July 1989

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British Journal of Clinical Pharmacology

19 October 2017

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19 October 2017

28

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19 October 2017

29-36

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19 October 2017

1

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Protein measurement with the Folin phenol reagent

19 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Evidence for an enzymatic defect in the 4-hydroxylation of debrisoquine by human liver

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Defective oxidation of drugs: pharmacokinetic and therapeutic implications

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Drug metabolism in human liver in vitro: establishment of a human liver bank.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Hepatic monooxygenase activities in subjects with a genetic defect in drug oxidation.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Inherited defects of hepatic drug metabolism

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Quinidine: potent inhibition of sparteine and debrisoquine oxidation in vivo.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Sparteine oxidation is practically abolished in quinidine-treated patients

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Pharmacogenetics of dextromethorphan O-demethylation in man.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Genetic variation in the human hepatic cytochrome P-450 system

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Polymorphic oxidation of debrisoquine and sparteine

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Determination of dextrorphan in plasma and evaluation of bioavailability of dextromethorphan hydrobromide in humans

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Polymorphic hydroxylation of Debrisoquine in man.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Inhibition of desmethylimipramine 2-hydroxylation by drugs in human liver microsomes.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Comparison of cytochrome P-450 content and activities in liver microsomes of seven animal species, including man.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1379967

Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugs

29 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1989.TB03502.X

Direct determination of dextromethorphan and its three metabolites in urine by high-performance liquid chromatography using a precolumn switching system for sample clean-up

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1989.TB03502.X

Quantitative determination of dextromethorphan and three metabolites in urine by reverse-phase high-performance liquid chromatography

21 January 2018

1 reference

12 December 2020

Dextromethorphan as a safe probe for debrisoquine hydroxylation polymorphism

1 reference

12 December 2020

In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase

1 reference

12 December 2020

Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

1 reference

12 December 2020

Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolizers

1 reference

12 December 2020

Debrisoquine/sparteine-type polymorphism of drug oxidation. Purification and characterization of two functionally different human liver cytochrome P-450 isozymes involved in impaired hydroxylation of the prototype substrate bufuralol

1 reference

12 December 2020

Oxidation of quinidine by human liver cytochrome P-450

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12 December 2020

Extensive metabolizers of debrisoquine become poor metabolizers during quinidine treatment

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12 December 2020

High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

1 reference

12 December 2020

High-performance liquid chromatographic determination of dextrorphan and 3-hydroxymorphinan in human plasma based on a selective pre-column sample clean-up

1 reference

12 December 2020

Determination of dextromethorphan in serum by gas chromatography

1 reference

12 December 2020

A program for non-linear regression analysis to be used on desk-top computers

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12 December 2020

10.1111/J.1365-2125.1989.TB03502.X

Identifiers

DOI

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19 October 2017

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19 October 2017

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