secretin (Q422301)

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mammalian protein found in Homo sapiens

RG1068
ChiRhoStim
SCT(28-54)

Language	Label	Description	Also known as
English	secretin	mammalian protein found in Homo sapiens	RG1068 ChiRhoStim SCT(28-54)

Statements

type of chemical entity

0 references

recombinant protein

0 references

1 reference

13 November 2019

UniProt protein ID

Glucagon/GIP/secretin/VIP, protein family

1 reference

based on heuristic

inferred from protein domain or family

prepro-secretin

0 references

1 reference

language of work or name

Secretin (English)

publication date

17 November 2015

biopharmaceutical

1 reference

language of work or name

Secretin (English)

publication date

17 November 2015

3,038.656703±0 dalton

1 reference

language of work or name

Secretin (human) (English)

21 September 2016

chemical formula

C₁₃₀H₂₂₀N₄₄O₄₀

1 reference

language of work or name

Secretin (human) (English)

21 September 2016

canonical SMILES

CC(C)CC(C(=O)NC(C(C)C)C(=O)N)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CC2=CNC=N2)N

1 reference

language of work or name

Secretin (human) (English)

21 September 2016

active ingredient in

1 reference

15 February 2018

World Health Organisation international non-proprietary name

Secretin (English)

1 reference

language of work or name

Secretin (English)

19 January 2016

1 reference

13 November 2019

UniProt protein ID

medical condition treated

8 April 2004

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/88C55N56UU

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021256s013lbl.pdf

exocrine pancreatic insufficiency

9 April 2004

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/88C55N56UU

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021256s013lbl.pdf

1 reference

13 November 2019

UniProt protein ID

molecular function

hormone activity

determination method

3 references

1 January 2018

Human secretin (SCT): gene structure, chromosome location, and distribution of mRNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

G protein-coupled receptor binding

determination method

1 reference

8 April 2019

Molecular cloning and functional characterization of a human secretin receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

signaling receptor binding

determination method

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09683&geneProductId=UniProtKB:P09683

determination method

protein N-terminus binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

hormone activity

determination method

5 references

8 April 2019

Human secretin (SCT): gene structure, chromosome location, and distribution of mRNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

extracellular space

determination method

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09683&geneProductId=UniProtKB:P09683

determination method

cellular component

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

extracellular space

determination method

3 references

biological process

brain development

determination method

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09683&geneProductId=UniProtKB:P09683

determination method

negative regulation of gastrin-induced gastric acid secretion

determination method

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09683&geneProductId=UniProtKB:P09683

determination method

pancreatic juice secretion

determination method

1 reference

8 April 2019

Human secretin (SCT): gene structure, chromosome location, and distribution of mRNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

embryonic digestive tract development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

positive regulation of somatostatin secretion

determination method

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09683&geneProductId=UniProtKB:P09683

determination method

positive regulation of pancreatic juice secretion

determination method

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P09683&geneProductId=UniProtKB:P09683

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

positive regulation of cAMP-mediated signaling

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

diet induced thermogenesis

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

hippocampus development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

response to nutrient levels

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

regulation of appetite

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

regulation of synaptic plasticity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

positive regulation of lipid catabolic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P09683

determination method

subject has role

gastrointestinal agent

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

protein fragment

prepro-secretin

0 references

NCI Thesaurus ID

C47713

1 reference

Global Substance Registration System

15 February 2018

C66531

1 reference

Global Substance Registration System

14 February 2018

https://www.uniprot.org/uniprot/P09683#PRO_0000011424

0 references

http://purl.uniprot.org/uniprot/P09683

reason for deprecated rank

cannot be confirmed by other sources

0 references

Glucagon/GIP/secretin/VIP

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P09683

Identifiers

InChI=1S/C130H220N44O40/c1-60(2)43-81(120(208)173-100(66(13)14)103(134)191)153-95(183)54-149-106(194)77(31-35-92(132)180)159-116(204)84(46-63(7)8)166-118(206)85(47-64(9)10)164-111(199)75(29-23-41-146-129(139)140)155-113(201)79(32-36-93(133)181)160-117(205)83(45-62(5)6)162-110(198)73(27-21-39-144-127(135)136)154-104(192)67(15)152-94(182)53-148-107(195)78(33-37-97(185)186)158-109(197)74(28-22-40-145-128(137)138)156-115(203)82(44-61(3)4)163-112(200)76(30-24-42-147-130(141)142)157-122(210)90(57-176)170-119(207)86(48-65(11)12)165-114(202)80(34-38-98(187)188)161-123(211)91(58-177)171-126(214)102(69(17)179)174-121(209)87(49-70-25-19-18-20-26-70)168-125(213)101(68(16)178)172-96(184)55-150-108(196)88(51-99(189)190)167-124(212)89(56-175)169-105(193)72(131)50-71-52-143-59-151-71/h18-20,25-26,52,59-69,72-91,100-102,175-179H,21-24,27-51,53-58,131H2,1-17H3,(H2,132,180)(H2,133,181)(H2,134,191)(H,143,151)(H,148,195)(H,149,194)(H,150,196)(H,152,182)(H,153,183)(H,154,192)(H,155,201)(H,156,203)(H,157,210)(H,158,197)(H,159,204)(H,160,205)(H,161,211)(H,162,198)(H,163,200)(H,164,199)(H,165,202)(H,166,206)(H,167,212)(H,168,213)(H,169,193)(H,170,207)(H,171,214)(H,172,184)(H,173,208)(H,174,209)(H,185,186)(H,187,188)(H,189,190)(H4,135,136,144)(H4,137,138,145)(H4,139,140,146)(H4,141,142,147)

1 reference

based on heuristic

inferred from SMILES

OWMZNFCDEHGFEP-NFBCVYDUSA-N

1 reference

language of work or name

Secretin (human) (English)

21 September 2016

CAS Registry Number

reason for deprecated rank

cannot be confirmed by other sources

0 references

1 reference

Global Substance Registration System

14 February 2018

1 reference

language of work or name

secretin human (English)

21 September 2016

1 reference

language of work or name

Secretin (human) (English)

21 September 2016

mapping relation type

1 reference

ChEBI release 2021-03-01

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

8 February 2021

1 reference

language of work or name

SECRETIN (English)

21 September 2016

UniChem compound ID

1 reference

215-733-3

1 reference

Global Substance Registration System

14 February 2018

ECHA Substance Infocard ID

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Secretin (English)

CAS no.: 1393-25-5 (English)

1 reference

language of work or name

Secretin (English)

publication date

17 November 2015

Guide to Pharmacology Ligand ID

0 references

MeSH descriptor ID

subject named as

Secretin

0 references

D06.472.317.800

0 references

D06.472.699.810

0 references

D12.644.400.705

0 references

D12.644.548.810

0 references

D12.776.631.650.705

0 references

1 reference

Global Substance Registration System

15 February 2018

1 reference

Global Substance Registration System

14 February 2018

1 reference

https://www.drugbank.ca/releases/latest#open-data

April 2018

reason for deprecated rank

deprecated identifier value

0 references

1 reference

Global Substance Registration System

15 February 2018

2 references

language of work or name

SECRETIN (English)

19 January 2016

Global Substance Registration System

14 February 2018

1 reference

language of work or name

SECRETIN (English)

19 January 2016

Probes And Drugs ID

0 references

1 reference

Brockhaus Enzyklopädie online ID

0 references

0 references

Encyclopædia Britannica Online ID

science/secretin

subject named as

secretin

author name string

Robert D. Utiger

0 references

1 reference

Freebase Data Dumps

publication date

28 October 2013

Gran Enciclopèdia Catalana ID

0 references

Gran Enciclopèdia Catalana ID (former scheme)

0 references

Great Russian Encyclopedia Online ID (old version)

subject named as

СЕКРЕТИН

reason for deprecated rank

redirected to GRE portal

0 references

Great Russian Encyclopedia portal ID

sekretin-948c4c

0 references

1 reference

9 July 2020

Microsoft Academic ID

0 references

0 references

NCI Drug Dictionary ID

0 references

0 references

Online PWN Encyclopedia ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

Proleksis enciklopedija ID

0 references

subject named as

secretina

1 reference

imported from Wikimedia project

Italian Wikipedia

Wikimedia import URL

https://it.wikipedia.org/w/index.php?title=Secretina&oldid=99526535

WikiSkripta article ID

0 references

Sitelinks

Wikipedia(36 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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