Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells (Q42232521)

19 October 2017

Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells (English)

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19 October 2017

multiple drug resistance

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Versantvoort CH

1

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19 October 2017

Schuurhuis GJ

2

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19 October 2017

Pinedo HM

3

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19 October 2017

Eekman CA

4

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19 October 2017

Kuiper CM

5

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19 October 2017

Lankelma J

6

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19 October 2017

Broxterman HJ

7

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19 October 2017

language of work or name

English

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publication date

1 November 1993

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British Journal of Cancer

19 October 2017

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19 October 2017

68

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19 October 2017

5

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19 October 2017

939-946

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https://scigraph.springernature.com/pub.10.1038/bjc.1993.458

19 October 2017

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cites work

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Phorbol esters induce multidrug resistance in human breast cancer cells

26 October 2017

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Genistein, a specific inhibitor of tyrosine-specific protein kinases

26 October 2017

1 reference

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Quantitative determination of factors contributing to doxorubicin resistance in multidrug-resistant cells

26 October 2017

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The biochemistry of P-glycoprotein-mediated multidrug resistance

26 October 2017

1 reference

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Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells

26 October 2017

1 reference

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Effect of calcium antagonists on the chemosensitivity of two multidrug-resistant human tumour cell lines which do not overexpress P-glycoprotein

26 October 2017

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Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II

26 October 2017

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Effects of the tyrosine-kinase inhibitor genistein on DNA synthesis and phospholipid-derived second messenger generation in mouse 10T1/2 fibroblasts and rat liver T51B cells

26 October 2017

1 reference

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Differential sensitivity of multi-drug-resistant and -sensitive cells to resistance-modifying agents and the relation with reversal of anthracycline resistance

26 October 2017

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Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction

26 October 2017

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Non-P-glycoprotein mediated mechanism for multidrug resistance precedes P-glycoprotein expression during in vitro selection for doxorubicin resistance in a human lung cancer cell line

26 October 2017

1 reference

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Binding of an optically pure photoaffinity analogue of verapamil, LU-49888, to P-glycoprotein from multidrug-resistant human leukemic cell lines

26 October 2017

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Reduced DNA topoisomerase II activity and drug-induced DNA cleavage activity in an adriamycin-resistant human small cell lung carcinoma cell line

26 October 2017

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Early multidrug resistance, defined by changes in intracellular doxorubicin distribution, independent of P-glycoprotein

26 October 2017

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Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy

26 October 2017

1 reference

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Establishment of a human leukemia subline resistant to the growth-inhibitory effect of 12-o-tetradecanoylphorbol 13-acetate (TPA) and showing non-P-glycoprotein-mediated multi-drug resistance

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Different mechanisms of decreased drug accumulation in doxorubicin and mitoxantrone resistant variants of the MCF7 human breast cancer cell line

26 October 2017

1 reference

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Transfection with protein kinase C alpha confers increased multidrug resistance to MCF-7 cells expressing P-glycoprotein

26 October 2017

1 reference

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Analysis of P-glycoprotein phosphorylation in HL60 cells isolated for resistance to vincristine

26 October 2017

1 reference

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Retention of activity by selected anthracyclines in a multidrug resistant human large cell lung carcinoma line without P-glycoprotein hyperexpression

26 October 2017

1 reference

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The antiproliferative effects of tyrosine kinase inhibitors tyrphostins on a human squamous cell carcinoma in vitro and in nude mice

26 October 2017

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Herbimycin A, an inhibitor of tyrosine kinase, prolongs survival of mice inoculated with myeloid leukemia C1 cells with high expression of v-abl tyrosine kinase

26 October 2017

1 reference

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Quantification by laser scan microscopy of intracellular doxorubicin distribution

26 October 2017

1 reference

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

26 October 2017

1 reference

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Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate

26 October 2017

1 reference

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Probing daunorubicin accumulation defects in non-P-glycoprotein expressing multidrug-resistant cell lines using digitonin

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines.

26 October 2017

1 reference

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Multifactorial drug resistance in an adriamycin-resistant human small cell lung carcinoma cell line

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Increase of daunorubicin and vincristine accumulation in multidrug resistant human ovarian carcinoma cells by a monoclonal antibody reacting with P-glycoprotein

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Pharmacological and biological evidence for differing mechanisms of doxorubicin resistance in two human tumor cell lines

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Correlation of MDR1 gene expression with chemotherapy in neuroblastoma.

29 May 2018

1 reference

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MDR1 gene expression in lung cancer.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Mechanisms of multidrug resistance in HL60 cells. Analysis of resistance associated membrane proteins and levels of mdr gene expression

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Overexpression of the mdr1 gene in blast cells from patients with acute myelocytic leukemia is associated with decreased anthracycline accumulation that can be restored by cyclosporin-A.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Mechanisms of multidrug resistance in HL60 cells: detection of resistance-associated proteins with antibodies against synthetic peptides that correspond to the deduced sequence of P-glycoprotein.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Regulation by phorbol ester and protein kinase C inhibitors, and by a protein phosphatase inhibitor (okadaic acid), of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Energy-dependent processes involved in reduced drug accumulation in multidrug-resistant human lung cancer cell lines without P-glycoprotein expression

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968712

17 August 2018

Identifiers

DOI

10.1038/BJC.1993.458

1 reference

19 October 2017

1 reference

19 October 2017

1 reference