Cervical cancer cell-derived interleukin-6 impairs CCR7-dependent migration of MMP-9-expressing dendritic cells. (Q42261545)

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28 February 2020

title

Cervical cancer cell-derived interleukin-6 impairs CCR7-dependent migration of MMP-9-expressing dendritic cells (English)

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28 February 2020

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cervix uterine cancer

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4

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28 February 2020

Barbara Walch-Rückheim

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object named as

Barbara Walch-Rückheim

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Jennifer Pahne-Zeppenfeld

28 February 2020

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object named as

Jennifer Pahne-Zeppenfeld

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28 February 2020

author name string

Nadine Schröer

2

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28 February 2020

Arko Gorter

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28 February 2020

Subramanya Hegde

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28 February 2020

Sigrun Smola

7

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28 February 2020

language of work or name

English

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publication date

1 May 2014

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International Journal of Cancer

28 February 2020

published in

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28 February 2020

volume

134

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28 February 2020

issue

9

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28 February 2020

page(s)

2061-2073

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A review of human carcinogens--Part B: biological agents

28 February 2020

cites work

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Human papillomavirus virus-like particles do not activate Langerhans cells: a possible immune escape mechanism used by human papillomaviruses

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Human papillomavirus type 8 interferes with a novel C/EBPβ-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhans cell migration.

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TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 16.

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The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter

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E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I.

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HPV-16 E5 down-regulates expression of surface HLA class I and reduces recognition by CD8 T cells.

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Epithelial cell responses to infection with human papillomavirus

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Molecular pathobiology of human cervical high-grade lesions: paracrine STAT3 activation in tumor-instructed myeloid cells drives local MMP-9 expression

21 January 2018

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M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells

21 January 2018

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Chemotherapy alters monocyte differentiation to favor generation of cancer-supporting M2 macrophages in the tumor microenvironment

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

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CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

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PGE2-induced metalloproteinase-9 is essential for dendritic cell migration

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Loss of IL-6 receptor expression in cervical carcinoma cells inhibits autocrine IL-6 stimulation: abrogation of constitutive monocyte chemoattractant protein-1 production

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Response to IL-6 of HPV-18 cervical carcinoma cell lines

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Efficient migration of dendritic cells toward lymph node chemokines and induction of T(H)1 responses require maturation stimulus and apoptotic cell interaction.

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CD40L induces matrix-metalloproteinase-9 but not tissue inhibitor of metalloproteinases-1 in cervical carcinoma cells: imbalance between NF-kappaB and STAT3 activation

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Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7

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Selective suppression of monocyte chemoattractant protein‐1 expression by human papillomavirus E6 and E7 oncoproteins in human cervical epithelial and epidermal cells

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Enhanced activation of CD83-positive T cells

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Up-regulation of the chemokine receptor CCR7 in classical but not in lymphocyte-predominant Hodgkin disease correlates with distinct dissemination of neoplastic cells in lymphoid organs

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Human papillomavirus 16-associated cervical intraepithelial neoplasia in humans excludes CD8 T cells from dysplastic epithelium

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Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

21 January 2018

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The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer

21 January 2018

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Randomised phase II study of siltuximab (CNTO 328), an anti-IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer

21 January 2018

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Interleukin-6 as a therapeutic target in human ovarian cancer

21 January 2018

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Pharmacokinetic and pharmacodynamic modeling of an anti-interleukin-6 chimeric monoclonal antibody (siltuximab) in patients with metastatic renal cell carcinoma

21 January 2018

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A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease

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Targeting the interleukin-6/Jak/stat pathway in human malignancies

21 January 2018

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Turning NF-kappaB and IRFs on and off in DC.

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Regulation of MMP-9 gene expression for the development of novel molecular targets against cancer and inflammatory diseases

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.28549

1 reference

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release_lcpcr4tuw5ghvn4n3ykkwbdeia

28 February 2020

Fatcat ID

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Fatcat

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24 November 2022

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