A human type 5 adenovirus-based tuberculosis vaccine induces robust T cell responses in humans despite preexisting anti-adenovirus immunity (Q42265160)

19 October 2017

A human type 5 adenovirus-based tuberculosis vaccine induces robust T cell responses in humans despite preexisting anti-adenovirus immunity (English)

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19 October 2017

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Jonathan Bramson

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author name string

Fiona Smaill

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19 October 2017

Mangalakumari Jeyanathan

2

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19 October 2017

Marek Smieja

3

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19 October 2017

Maria Fe Medina

4

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19 October 2017

Niroshan Thanthrige-Don

5

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19 October 2017

Anna Zganiacz

6

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19 October 2017

Cindy Yin

7

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19 October 2017

Armando Heriazon

8

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19 October 2017

Daniela Damjanovic

9

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19 October 2017

Laura Puri

10

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19 October 2017

Jemila Hamid

11

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19 October 2017

Feng Xie

12

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19 October 2017

Ronan Foley

13

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19 October 2017

Jack Gauldie

15

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19 October 2017

Zhou Xing

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19 October 2017

language of work or name

English

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publication date

1 October 2013

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Science Translational Medicine

19 October 2017

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19 October 2017

5

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19 October 2017

205

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19 October 2017

205ra134

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Tuberculosis vaccines: a strategic blueprint for the next decade

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Fact and fiction in tuberculosis vaccine research: 10 years later

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Tuberculosis vaccines in clinical trials

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Heterologous boost vaccines for bacillus Calmette-Guérin prime immunization against tuberculosis

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TB vaccines: current status and future perspectives

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Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis

21 January 2018

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Recent advances in the development of adenovirus- and poxvirus-vectored tuberculosis vaccines.

21 January 2018

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Viral vectors as vaccine platforms: deployment in sight

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New insights on adenovirus as vaccine vectors

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CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates

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Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans.

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Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component

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Mechanisms of mucosal and parenteral tuberculosis vaccinations: adenoviral-based mucosal immunization preferentially elicits sustained accumulation of immune protective CD4 and CD8 T cells within the airway lumen

21 January 2018

1 reference

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Intranasal mucosal boosting with an adenovirus-vectored vaccine markedly enhances the protection of BCG-primed guinea pigs against pulmonary tuberculosis

21 January 2018

1 reference

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Goats primed with Mycobacterium bovis BCG and boosted with a recombinant adenovirus expressing Ag85A show enhanced protection against tuberculosis

21 January 2018

1 reference

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Immune responses induced in cattle by vaccination with a recombinant adenovirus expressing Mycobacterial antigen 85A and Mycobacterium bovis BCG

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1 reference

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Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

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Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity

21 January 2018

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Seroprevalence of neutralizing antibodies to adenovirus type 5 among children in India: implications for recombinant adenovirus-based vaccines

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Use of recombinant virus-vectored tuberculosis vaccines for respiratory mucosal immunization

21 January 2018

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Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species

21 January 2018

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Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon

21 January 2018

1 reference

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Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys

21 January 2018

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HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis

21 January 2018

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The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults

21 January 2018

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Safety and immunogenicity of adenovirus-vectored near-consensus HIV type 1 clade B gag vaccines in healthy adults

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Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa

21 January 2018

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Murine airway luminal antituberculosis memory CD8 T cells by mucosal immunization are maintained via antigen-driven in situ proliferation, independent of peripheral T cell recruitment.

21 January 2018

1 reference

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Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans

21 January 2018

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Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in Mycobacterium tuberculosis-infected individuals

21 January 2018

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T cells in mycobacterial infection and disease

21 January 2018

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Bacillus Calmette-Guérin vaccination of human newborns induces T cells with complex cytokine and phenotypic profiles

21 January 2018

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A comparison of IFNgamma detection methods used in tuberculosis vaccine trials

21 January 2018

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Safety and Immunogenicity of a Replication‐Incompetent Adenovirus Type 5 HIV‐1 Clade Bgag/pol/nefVaccine in Healthy Adults

21 January 2018

1 reference

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10.1126/SCITRANSLMED.3006843

21 January 2018

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DOI

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19 October 2017

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