Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch (Q42275889)

19 October 2017

Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch (English)

1 reference

19 October 2017

Marco Fischer

4

0 references

Bojana Durovic

object named as

Bojana Durovic

7

0 references

Sarah Dimeloe

object named as

Sarah Dimeloe

5

0 references

author name string

Patrick M Gubser

1

1 reference

19 October 2017

Glenn R Bantug

2

1 reference

19 October 2017

Leyla Razik

3

1 reference

19 October 2017

Gideon Hoenger

6

1 reference

19 October 2017

Annaïse Jauch

8

1 reference

19 October 2017

Christoph Hess

9

1 reference

19 October 2017

language of work or name

English

0 references

publication date

18 August 2013

1 reference

19 October 2017

1 reference

19 October 2017

14

1 reference

19 October 2017

1064-1072

1 reference

19 October 2017

10

1 reference

Inflaming the CD8+ T cell response.

19 October 2017

1 reference

Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection

21 January 2018

1 reference

Fuel feeds function: energy metabolism and the T-cell response

21 January 2018

1 reference

Homeostatic control of lymphocyte survival: potential origins and implications

21 January 2018

1 reference

Regulation of T lymphocyte metabolism

21 January 2018

1 reference

The CD28 signaling pathway regulates glucose metabolism

21 January 2018

1 reference

Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.

21 January 2018

1 reference

Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival

21 January 2018

1 reference

Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells

21 January 2018

1 reference

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

21 January 2018

1 reference

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

21 January 2018

1 reference

Hidden memories: frontline memory T cells and early pathogen interception

21 January 2018

1 reference

Dynamics of blood-borne CD8 memory T cell migration in vivo.

21 January 2018

1 reference

Preferential localization of effector memory cells in nonlymphoid tissue

21 January 2018

1 reference

Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets

21 January 2018

1 reference

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

21 January 2018

1 reference

Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

21 January 2018

1 reference

Subcellular dynamics of multifunctional protein regulation: mechanisms of GAPDH intracellular translocation

21 January 2018

1 reference

Subcellular localization of human glyceraldehyde-3-phosphate dehydrogenase is independent of its glycolytic function

21 January 2018

1 reference

Effects of hypoxia and/or lack of glucose on cellular energy metabolism and cytokine production in stimulated human CD4+ T lymphocytes

21 January 2018

1 reference

PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans

21 January 2018

1 reference

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

21 January 2018

1 reference

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

21 January 2018

1 reference

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

21 January 2018

1 reference

Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin

21 January 2018

1 reference

Diversity in T cell memory: an embarrassment of riches

21 January 2018

1 reference

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

21 January 2018

1 reference

Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure

21 January 2018

1 reference

Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells

21 January 2018

1 reference

Posttranscriptional control of T cell effector function by aerobic glycolysis

21 January 2018

1 reference

Direct visualization of cytokine-producing recall antigen-specific CD4 memory T cells in healthy individuals and HIV patients.

21 January 2018

1 reference

Sirtuin 1 in immune regulation and autoimmunity

21 January 2018

1 reference

Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8(+) T-cell response

21 January 2018

1 reference

The molecular basis of the memory T cell response: differential gene expression and its epigenetic regulation

21 January 2018

1 reference

Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression.

21 January 2018

1 reference

Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status

21 January 2018

1 reference

ATP-citrate lyase links cellular metabolism to histone acetylation

21 January 2018

1 reference

Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells

21 January 2018

1 reference

Memory CD8+ T cells require CD28 costimulation.

21 January 2018

1 reference

The role of CD80/CD86 in generation and maintenance of functional virus-specific CD8+ T cells in mice infected with lymphocytic choriomeningitis virus

21 January 2018

1 reference

Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c

21 January 2018

1 reference

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

21 January 2018

1 reference

Upregulation of the transcript level of GTPase activating protein KIAA0603 in T cells from patients with atopic dermatitis.

21 January 2018

1 reference

Metabolic regulation of epigenetics

21 January 2018

1 reference

Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot"

21 January 2018

1 reference

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

21 January 2018

1 reference

12 December 2020

Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines

1 reference

12 December 2020

Glucose is essential for proliferation and the glycolytic enzyme induction that provokes a transition to glycolytic energy production

1 reference

12 December 2020

Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.2687

1 reference

19 October 2017

1 reference