Transcript signatures that predict outcome and identify targetable pathways in MYCN-amplified neuroblastoma (Q42282780)

19 October 2017

Transcript signatures that predict outcome and identify targetable pathways in MYCN-amplified neuroblastoma (English)

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19 October 2017

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Robin M Hallett

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19 October 2017

Alex B K Seong

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19 October 2017

David R Kaplan

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19 October 2017

Meredith S Irwin

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19 October 2017

18 August 2016

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19 October 2017

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19 October 2017

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19 October 2017

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19 October 2017

1461-1472

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describes a project that uses

19 October 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

cites work

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26 October 2017

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DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

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Alternative NHEJ Pathway Components Are Therapeutic Targets in High-Risk Neuroblastoma

26 October 2017

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The REST gene signature predicts drug sensitivity in neuroblastoma cell lines and is significantly associated with neuroblastoma tumor stage.

26 October 2017

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26 October 2017

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Validation of a prognostic multi-gene signature in high-risk neuroblastoma using the high throughput digital NanoString nCounter™ system

26 October 2017

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A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma

26 October 2017

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26 October 2017

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26 October 2017

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snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis.

26 October 2017

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A NOTCH3 transcriptional module induces cell motility in neuroblastoma

26 October 2017

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Targeting MYCN in neuroblastoma by BET bromodomain inhibition

26 October 2017

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The genetic landscape of high-risk neuroblastoma

26 October 2017

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Children's Oncology Group's 2013 blueprint for research: neuroblastoma

26 October 2017

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26 October 2017

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Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification

26 October 2017

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Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project

26 October 2017

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Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma

26 October 2017

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A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Activated ALK collaborates with MYCN in neuroblastoma pathogenesis.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

A gene signature for predicting outcome in patients with basal-like breast cancer

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

A three-gene expression signature model for risk stratification of patients with neuroblastoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Most random gene expression signatures are significantly associated with breast cancer outcome

26 October 2017

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A 6-gene signature identifies four molecular subgroups of neuroblastoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Identification of multiple hypoxia signatures in neuroblastoma cell lines by l1-l2 regularization and data reduction

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

A human functional protein interaction network and its application to cancer data analysis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signature

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Reanalysis of neuroblastoma expression profiling data using improved methodology and extended follow-up increases validity of outcome prediction

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Differential expression of neuronal genes defines subtypes of disseminated neuroblastoma with favorable and unfavorable outcome

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Adjusting batch effects in microarray expression data using empirical Bayes methods

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Chromosome 1p and 11q deletions and outcome in neuroblastoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Prognostic significance of DNA di-tetraploidy in neuroblastoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Targeted expression of MYCN causes neuroblastoma in transgenic mice

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

myc gene amplification and expression in primary human neuroblastoma

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

SATB2 enhances migration and invasion in osteosarcoma by regulating genes involved in cytoskeletal organization.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

The prognostic ease and difficulty of invasive breast carcinoma.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate risk neuroblastomas.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Recent advances in neuroblastoma

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5423212

Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas

30 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2016.07.012

Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2016.07.012

59-gene prognostic signature sub-stratifies high-risk neuroblastoma patients

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2016.07.012

Accumulation of Segmental Alterations Determines Progression in Neuroblastoma

21 January 2018

1 reference

12 December 2020

Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma

1 reference

12 December 2020

Gene-expression-based analysis of local and metastatic neuroblastoma variants reveals a set of genes associated with tumor progression in neuroblastoma patients

1 reference

12 December 2020

Additional copies of a 25 Mb chromosomal region originating from 17q23.1-17qter are present in 90% of high-grade neuroblastomas

1 reference

12 December 2020

Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma

1 reference

12 December 2020

10.1016/J.MOLONC.2016.07.012

Identifiers

DOI

1 reference

19 October 2017

1 reference

19 October 2017

PubMed publication ID

27599694

1 reference