eplerenone (Q423804)

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steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure
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Language Label Description Also known as
English
eplerenone
steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure

    Statements

    has use
    medication
    0 references
    mass
    414.204239±0 dalton
    1 reference
    stated in
    PubChem
    PubChem CID
    150310
    language of work or name
    English
    title
    Epoxymexrenone (English)
    retrieved
    21 September 2016
    chemical formula
    C₂₄H₃₀O₆
    1 reference
    stated in
    PubChem
    PubChem CID
    150310
    language of work or name
    English
    title
    Epoxymexrenone (English)
    retrieved
    21 September 2016
    canonical SMILES
    CC12CCC(=O)C=C1CC(C3C24C(O4)CC5(C3CCC56CCC(=O)O6)C)C(=O)OC
    1 reference
    stated in
    PubChem
    retrieved
    19 February 2019
    title
    Eplerenone (English)
    PubChem CID
    443872
    isomeric SMILES
    COC(=O)[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@@]34O[C@@H]3C[C@@]5(C)[C@@H](CC[C@@]56CCC(=O)O6)[C@H]14
    1 reference
    stated in
    Global Substance Registration System
    UNII
    6995V82D0B
    retrieved
    15 February 2018
    C[C@]12CCC(=O)C=C1C[C@H]([C@@H]3[C@]24[C@H](O4)C[C@]5([C@H]3CC[C@@]56CCC(=O)O6)C)C(=O)OC
    1 reference
    stated in
    PubChem
    retrieved
    19 February 2019
    title
    Eplerenone (English)
    PubChem CID
    443872
    significant drug interaction
    legal status (medicine)
    boxed warning
    1 reference
    reference URL
    https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
    title
    FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)
    Commons category
    Eplerenone
    0 references

    Identifiers

    ChemSpider ID
    132492
    1 reference
    stated in
    ChemSpider
    ChemSpider ID
    132492
    language of work or name
    English
    title
    Methyl (4aS,4bR,6aS,7R,9aS,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[7,8]phenanthro[4b,5-b]oxirene-7,2'-furan]-10-carboxylate (English)
    retrieved
    21 September 2016
    PubChem CID
    443872
    1 reference
    stated in
    PubChem
    retrieved
    19 February 2019
    title
    Eplerenone (English)
    PubChem CID
    443872
    HSDB ID
    7522
    1 reference
    stated in
    Hazardous Substances Data Bank
    HSDB ID
    7522
    publication date
    28 October 2019
    title
    EPLERENONE (English)
    retrieved
    10 May 2021
    LiverTox ID
    Eplerenone
    0 references
    EC number
    600-850-8
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.106.615
    retrieved
    27 December 2018
    title
    Methyl (4aS,5aR,6aS,7S,9aS,9bR,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'Hspiro[cyclopenta[1,2]phenanthro[4,4ab]oxirene-7,2'-furan]-10-carboxylate (English)
    quotation
    CAS no.: 107724-20-9 (English)
    ECHA Substance Infocard ID
    100.106.615
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.106.615
    retrieved
    27 December 2018
    title
    Methyl (4aS,5aR,6aS,7S,9aS,9bR,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'Hspiro[cyclopenta[1,2]phenanthro[4,4ab]oxirene-7,2'-furan]-10-carboxylate (English)
    quotation
    CAS no.: 107724-20-9 (English)
    ATC code
    C03DA04
    0 references
    DrugBank ID
    00700
    0 references
    PDB ligand ID
    YNU
    0 references
     
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