Vinculin (Q424042)

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mammalian protein found in Homo sapiens
  • epididymis secretory sperm binding protein
  • epididymis luminal protein 114
  • vinculin
  • metavinculin
  • VCL
  • meta-vinculin
  • MV
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Language Label Description Also known as
English
Vinculin
mammalian protein found in Homo sapiens
  • epididymis secretory sperm binding protein
  • epididymis luminal protein 114
  • vinculin
  • metavinculin
  • VCL
  • meta-vinculin
  • MV

Statements

molecular function
protein binding
determination method
IPI
17 references
retrieved
31 October 2017
stated in
Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Human alpha-synemin interacts directly with vinculin and metavinculin
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Integrin-mediated cell adhesion: the cytoskeletal connection
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Structural dynamics of alpha-actinin-vinculin interactions
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Structural basis for amplifying vinculin activation by talin
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Dimer asymmetry defines α-catenin interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Raver1 Interactions with Vinculin and RNA Suggest a Feed-Forward Pathway in Directing mRNA to Focal Adhesions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Capping of actin filaments by vinculin activated by the Shigella IpaA carboxyl-terminal domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Vinculin binding in its closed conformation by a helix addition mechanism
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motility
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
retrieved
31 October 2017
stated in
Role of dystrophins and utrophins in platelet adhesion process
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IPI
cell component
focal adhesion
determination method
IDA
ISS
IEA
6 references
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
ISS
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IEA
retrieved
31 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IEA
retrieved
31 October 2017
stated in
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
GOA
curator
UniProt
UniProt protein ID
P18206
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IDA
retrieved
31 October 2017
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IDA
retrieved
31 October 2017
stated in
Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206
determination method
IDA
biological process
Gene Atlas image
PBB GE VCL 200931 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

PDB structure ID
 
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