Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale. (Q42408230)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20497038%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale (English)

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3 February 2020

6

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3 February 2020

James Wilson

7

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3 February 2020

author name string

Martin Lock

1

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3 February 2020

Mauricio Alvira

2

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3 February 2020

Luk H Vandenberghe

3

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3 February 2020

Arabinda Samanta

4

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3 February 2020

Jaan Toelen

5

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3 February 2020

publication date

1 October 2010

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3 February 2020

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3 February 2020

volume

21

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3 February 2020

issue

10

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3 February 2020

page(s)

1259-1271

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describes a project that uses

3 February 2020

ImageJ

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11 June 2022

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based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Clinical gene therapy using recombinant adeno-associated virus vectors

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High-titer, serum-free production of adeno-associated virus vectors by polyethyleneimine-mediated plasmid transfection in mammalian suspension cells

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Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells

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Production and characterization of adeno-associated viral vectors

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Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors

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Treatment of human disease by adeno-associated viral gene transfer

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Quantification of adeno-associated virus particles and empty capsids by optical density measurement

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Production of clinical-grade recombinant adeno-associated virus vectors

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A versatile and scalable two-step ion-exchange chromatography process for the purification of recombinant adeno-associated virus serotypes-2 and -5.

28 May 2018

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28 May 2018

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28 May 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20497038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/HUM.2010.055

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20497038%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

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3 February 2020

1 reference