Cholesterol and sphingomyelin drive ligand-independent T-cell antigen receptor nanoclustering (Q42410761)

30 October 2017

Cholesterol and sphingomyelin drive ligand-independent T-cell antigen receptor nanoclustering (English)

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30 October 2017

8

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30 October 2017

Mahima Swamy

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Wolfgang Schamel

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object named as

Wolfgang W A Schamel

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30 October 2017

Katharina Beck-García

4

object named as

Katharina Beck-García

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30 October 2017

1

Eszter Molnár

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Petra Schwille

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object named as

Petra Schwille

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30 October 2017

Eszter Molnár

1

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30 October 2017

Martin Holzer

3

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30 October 2017

Remigiusz Worch

5

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30 October 2017

Christoph Thiele

6

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30 October 2017

Gernot Guigas

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30 October 2017

Immanuel F Luescher

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30 October 2017

Rolf Schubert

11

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30 October 2017

language of work or name

English

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publication date

22 October 2012

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Journal of Biological Chemistry

30 October 2017

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30 October 2017

287

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30 October 2017

42664-42674

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30 October 2017

51

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describes a project that uses

30 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3522267/fullTextXML

inferred from PubMed Central ID database lookup

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28 May 2018

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Oligomeric organization of the B-cell antigen receptor on resting cells

28 May 2018

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Stoichiometry and intracellular fate of TRIM-containing TCR complexes

28 May 2018

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28 May 2018

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TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation.

28 May 2018

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A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels

28 May 2018

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T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity

28 May 2018

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28 May 2018

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Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response

28 May 2018

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Paradigm Shift of the Plasma Membrane Concept from the Two-Dimensional Continuum Fluid to the Partitioned Fluid: High-Speed Single-Molecule Tracking of Membrane Molecules

28 May 2018

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Electron crystallography reveals the structure of metarhodopsin I.

28 May 2018

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Nanoscale organization of multiple GPI-anchored proteins in living cell membranes.

28 May 2018

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The roles of membrane microdomains (rafts) in T cell activation

28 May 2018

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An evolutionary and structural perspective on T cell antigen receptor function

28 May 2018

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28 May 2018

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Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells

28 May 2018

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28 May 2018

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One-step purification of recombinant proteins using a nanomolar-affinity streptavidin-binding peptide, the SBP-Tag

28 May 2018

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Cutting edge: lipid raft integrity affects the efficiency of MHC class I tetramer binding and cell surface TCR arrangement on CD8+ T cells

28 May 2018

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Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen

28 May 2018

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Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

28 May 2018

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Multivalent structure of an alphabetaT cell receptor

28 May 2018

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Lipid patches in membrane protein oligomers: crystal structure of the bacteriorhodopsin-lipid complex

28 May 2018

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Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

28 May 2018

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Functional rafts in cell membranes

28 May 2018

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Evidence for multivalent structure of T-cell antigen receptor complex

28 May 2018

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Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes.

28 May 2018

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Molecular recognition of a single sphingolipid species by a protein's transmembrane domain.

16 August 2018

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Increased sensitivity of antigen-experienced T cells through the enrichment of oligomeric T cell receptor complexes.

16 August 2018

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Anatomy and dynamics of a supramolecular membrane protein cluster.

16 August 2018

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Blue native polyacrylamide gel electrophoresis (BN-PAGE) for the identification and analysis of multiprotein complexes.

16 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522267

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522267

Revaluation of the role of cholesterol in stabilizing rafts implicated in T cell receptor signaling

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522267

A physical and functional link between cholesterol and tetraspanins

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522267

Molecular and functional profiling of memory CD8 T cell differentiation.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522267

Interaction of cholesterol with sphingomyelin in mixed membranes containing phosphatidylcholine, studied by spin-label ESR and IR spectroscopies. A possible stabilization of gel-phase sphingolipid domains by cholesterol

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522267

Ligand recognition by alpha beta T cell receptors

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522267

CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.386045

N- and O-methylation of sphingomyelin markedly affects its membrane properties and interactions with cholesterol

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.386045

Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals

21 January 2018

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12 December 2020

Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3

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12 December 2020

The preferential interaction of cholesterol with different classes of phospholipids

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12 December 2020

Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern

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12 December 2020

Identifiers

DOI

10.1074/JBC.M112.386045

1 reference

30 October 2017

1 reference

30 October 2017

1 reference