Novel interactions of CLN3 protein link Batten disease to dysregulation of fodrin-Na+, K+ ATPase complex. (Q42438650)

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10 January 2020

title

Novel interactions of CLN3 protein link Batten disease to dysregulation of fodrin-Na+, K+ ATPase complex (English)

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Ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)

10 January 2020

main subject

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GOA release 2020-03-11

author

Kaisu Luiro

2

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10 January 2020

Pablo Martín-Vasallo

5

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10 January 2020

author name string

Kristiina Uusi-Rauva

1

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10 January 2020

Kimmo Tanhuanpää

3

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10 January 2020

Outi Kopra

4

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10 January 2020

Aija Kyttälä

6

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10 January 2020

Anu Jalanko

7

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10 January 2020

language of work or name

English

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publication date

28 June 2008

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Experimental Cell Research

10 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18621045%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

314

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10 January 2020

issue

15

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10 January 2020

page(s)

2895-2905

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The neuronal ceroid-lipofuscinoses: from past to present

10 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Isolation of a novel gene underlying batten disease, CLN3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Characterization of Cln3p, the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

C-terminal prenylation of the CLN3 membrane glycoprotein is required for efficient endosomal sorting to lysosomes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

The transmembrane topology of Batten disease protein CLN3 determined by consensus computational prediction constrained by experimental data

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Membrane topology of CLN3, the protein underlying Batten disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

The equilibrative nucleoside transporter family, SLC29

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

CLN3P, the Batten's disease protein, is a novel palmitoyl-protein Delta-9 desaturase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Biosynthesis and intracellular targeting of the CLN3 protein defective in Batten disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

btn1, the Schizosaccharomyces pombe homologue of the human Batten disease gene CLN3, regulates vacuole homeostasis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Apoptosis as the mechanism of neurodegeneration in Batten's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

A novel role of the Batten disease gene CLN3: association with BMP synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Neuronal vulnerability of CLN3 deletion to calcium-induced cytotoxicity is mediated by calsenilin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Elevated lysosomal pH in neuronal ceroid lipofuscinoses (NCLs)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Action of BTN1, the yeast orthologue of the gene mutated in Batten disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

A role in vacuolar arginine transport for yeast Btn1p and for human CLN3, the protein defective in Batten disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Defective lysosomal arginine transport in juvenile Batten disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Batten disease (JNCL) is linked to disturbances in mitochondrial, cytoskeletal, and synaptic compartments.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Visual deficits in a mouse model of Batten disease are the result of optic nerve degeneration and loss of dorsal lateral geniculate thalamic neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Expression of the beta-subunit isoforms of the Na,K-ATPase in rat embryo tissues, inner ear and choroid plexus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Targeted disruption of the Cln3 gene provides a mouse model for Batten disease. The Batten Mouse Model Consortium [corrected]

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Expression of palmitoyl protein thioesterase in neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Identification of a transactivation motif in the CLN3 protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Ankyrin links fodrin to the alpha subunit of Na,K-ATPase in Madin-Darby canine kidney cells and in intact renal tubule cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

CLN3L, a novel protein related to the Batten disease protein, is overexpressed in Cln3-/- mice and in Batten disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Degradation and endoplasmic reticulum retention of unassembled alpha- and beta-subunits of Na,K-ATPase correlate with interaction of BiP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

The C-terminal domain of Drosophila (beta) heavy-spectrin exhibits autonomous membrane association and modulates membrane area

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Brush border spectrin is required for early endosome recycling in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Elevation of Hook1 in a disease model of Batten disease does not affect a novel interaction between Ankyrin G and Hook1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Analysis of Na+,K+-ATPase motion and incorporation into the plasma membrane in response to G protein-coupled receptor signals in living cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Functional biology of the neuronal ceroid lipofuscinoses (NCL) proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Synapsin I-mediated interaction of brain spectrin with synaptic vesicles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

The domain of brain beta-spectrin responsible for synaptic vesicle association is essential for synaptic transmission

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

CLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles: new clues to Batten disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Axons break in animals lacking beta-spectrin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

beta-Spectrin functions independently of Ankyrin to regulate the establishment and maintenance of axon connections in the Drosophila embryonic CNS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Distinct functions of alpha-Spectrin and beta-Spectrin during axonal pathfinding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Presynaptic spectrin is essential for synapse stabilization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

A postsynaptic spectrin scaffold defines active zone size, spacing, and efficacy at the Drosophila neuromuscular junction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Drosophila alpha- and beta-spectrin mutations disrupt presynaptic neurotransmitter release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Functional categorization of gene expression changes in the cerebellum of a Cln3-knockout mouse model for Batten disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Early changes in gene expression in two models of Batten disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

New roles for an old enzyme: Na,K-ATPase emerges as an interesting drug target

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Ouabain induces endocytosis of plasmalemmal Na/K-ATPase in LLC-PK1 cells by a clathrin-dependent mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Ouabain-induced endocytosis of the plasmalemmal Na/K-ATPase in LLC-PK1 cells requires caveolin-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

GRP78/BIP is involved in ouabain-induced endocytosis of the Na/K-ATPase in LLC-PK1 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Cell signaling microdomain with Na,K-ATPase and inositol 1,4,5-trisphosphate receptor generates calcium oscillations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activation of NF-kappaB

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Na,K-ATPase generates calcium oscillations in hippocampal astrocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Contacts and cooperation between cells depend on the hormone ouabain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Regulation of endocytic pH by the Na+,K+-ATPase in living cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

A possible role for Na+,K+-ATPase in regulating ATP-dependent endosome acidification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Second messengers regulate endosomal acidification in Swiss 3T3 fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Cellubrevin-targeted fluorescence uncovers heterogeneity in the recycling endosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

Role of endosomal Na+-K+-ATPase and cardiac steroids in the regulation of endocytosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.06.016

10.1016/J.YEXCR.2008.06.016

7 January 2021

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10 January 2020

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