ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis. (Q42443548)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12821943%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis (English)

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5 November 2019

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2

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5 November 2019

Zeev Ronai

series ordinal

4

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5 November 2019

author name string

Mikhail Krasilnikov

series ordinal

1

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5 November 2019

Jinali Dong

series ordinal

3

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5 November 2019

language of work or name

English

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publication date

1 June 2003

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5 November 2019

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5 November 2019

volume

22

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5 November 2019

page(s)

4092-4101

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5 November 2019

issue

26

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206598

5 November 2019

exact match

0 references

cites work

A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

21 January 2018

1 reference

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Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

Contribution of phosphatidylinositol 3-kinase to radiation resistance in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

Serine phosphorylation and negative regulation of Stat3 by JNK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

Inhibition of cytokines and JAK-STAT activation by distinct signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

Functionally distinct isoforms of STAT5 are generated by protein processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

1 reference

7 January 2021

The role of STATs in transcriptional control and their impact on cellular function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Specific inhibition of Stat3 signal transduction by PIAS3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

STATs and gene regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Mutations of the BRAF gene in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Cytokine receptor signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Cooperation between STAT3 and c-jun suppresses Fas transcription.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Pleiotropic effects of Bcl-2 on transcription factors in T cells: potential role of NF-kappa B p50-p50 for the anti-apoptotic function of Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Regulation of STAT3 by direct binding to the Rac1 GTPase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206598

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206598

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12821943%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 November 2019

0 references

1 reference