Drug metabolism in hepatocyte sandwich cultures of rats and humans (Q42446290)

31 October 2017

Drug metabolism in hepatocyte sandwich cultures of rats and humans (English)

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31 October 2017

Kern A

1

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31 October 2017

Bader A

series ordinal

2

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31 October 2017

Pichlmayr R

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3

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31 October 2017

Sewing KF

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4

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31 October 2017

language of work or name

English

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publication date

1 October 1997

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31 October 2017

Biochemical Pharmacology

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31 October 2017

54

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31 October 2017

7

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31 October 2017

761-772

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The isoenzyme pattern of cytochrome P450 in rat hepatocytes in primary culture, comparing different enzyme activities in microsomal incubations and in intact monolayers

31 October 2017

1 reference

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A Microassay for Measuring Cytochrome P450IA1 and Cytochrome P450IIB1 Activities in Intact Human and Rat Hepatocytes Cultured on 96-Well Plates

7 January 2021

1 reference

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Problems in using isolated and cultured hepatocytes for xenobiotic metabolism/metabolism-based toxicity testing-Solutions?

7 January 2021

1 reference

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Reconstruction of liver tissue in vitro: geometry of characteristic flat bed, hollow fiber, and spouted bed bioreactors with reference to the in vivo liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Use of organotypical cultures of primary hepatocytes to analyse drug biotransformation in man and animals

7 January 2021

1 reference

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Species differences in metabolism and pharmacokinetics: are we close to an understanding?

7 January 2021

1 reference

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Collagen substrata for studies on cell behavior

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

7 January 2021

1 reference

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Interlaboratory comparison of microsomal ethoxyresorufin and pentoxyresorufin O-dealkylation determinations: standardization of assay conditions

7 January 2021

1 reference

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An alternative 7-ethoxyresorufin O-deethylase activity assay: a continuous visible spectrophotometric method for measurement of cytochrome P-450 monooxygenase activity

7 January 2021

1 reference

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Cytosol-mediated reduction of resorufin fluorescence: effects on the ethoxyresorufin O-deethylase (ETR) assay

7 January 2021

1 reference

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The O-Dealkylation of 7-Ethoxycoumarin by Liver Microsomes. A Direct Fluorometric Test

7 January 2021

1 reference

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7-Ethoxycoumarin O-deethylase induction by phenobarbitone and 1,2-benzanthracene in primary maintenance cultures of adult rat hepatocytes

7 January 2021

1 reference

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Selective induction and inhibition of the components of 7-ethoxycoumarin O-deethylase activity in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450.

7 January 2021

1 reference

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Methods for the quantitation of bromosulfophthalein and its glutathione conjugate in biological fluids

7 January 2021

1 reference

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Cytochrome P450 activities in pure and co-cultured rat hepatocytes. Effects of model inducers

7 January 2021

1 reference

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7-Ethoxycoumarin O-deethylase kinetics in isolated rat, dog and human hepatocyte suspensions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Maintenance of mixed-function oxidase and conjugation enzyme activities in hepatocyte cultures prepared from normal and diseased human liver

7 January 2021

1 reference

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Prolonged expression of biotransformation activities of rat hepatocytes co-cultured with established cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Effect of xenobiotics on monooxygenase activities in cultured human hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Effect of culture age on drug metabolizing enzymes and their induction in primary cultures of rat hepatocytes

7 January 2021

1 reference

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Measurement of enzyme activities of cytochrome P-450 isoenzymes by high-performance liquid chromatographic analysis of products

7 January 2021

1 reference

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Species differences of testosterone 16-hydroxylases in liver microsomes of guinea pig, rat and dog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Physiological and pathophysiological alterations in rat hepatic cytochrome P-450.

7 January 2021

1 reference

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Phenobarbital induction of cytochromes P-450. High-level long-term responsiveness of primary rat hepatocyte cultures to drug induction, and glucocorticoid dependence of the phenobarbital response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Effect of periportal- and centrilobular-equivalent oxygen tension on liver specific functions in long-term rat hepatocyte cultures.

7 January 2021

1 reference

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Evaluation of the xenobiotic biotransformation capability of six rodent hepatoma cell lines in comparison with rat hepatocytes

7 January 2021

1 reference

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Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression

7 January 2021

1 reference

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Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Human adult hepatocytes in primary monolayer culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

Advantages and disadvantages of using human cells for pharmacological and toxicological studies

7 January 2021

1 reference

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33 Induction protocols for cytochromes P450IIIA in Vivo and in primary cultures of animal and human hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900204-9

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

7 January 2021

1 reference

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Sex-difference and the effects of smoking and oral contraceptive steroids on the kinetics of diflunisal

7 January 2021

1 reference

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10.1016/S0006-2952(97)00204-9

7 January 2021

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DOI

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31 October 2017

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