Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress (Q42451739)

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scientific article published on 14 July 2010

Language	Label	Description	Also known as
English	Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress	scientific article published on 14 July 2010

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scholarly article

1 reference

Europe PubMed Central

31 October 2017

Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress (English)

1 reference

Europe PubMed Central

31 October 2017

endoplasmic reticulum

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0 references

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Keisuke Yamamoto

1

1 reference

Europe PubMed Central

31 October 2017

Kazuna Takahara

2

1 reference

Europe PubMed Central

31 October 2017

Seiichi Oyadomari

3

1 reference

Europe PubMed Central

31 October 2017

Tetsuya Okada

4

1 reference

Europe PubMed Central

31 October 2017

Takashi Sato

5

1 reference

Europe PubMed Central

31 October 2017

Akihiro Harada

6

1 reference

Europe PubMed Central

31 October 2017

Kazutoshi Mori

7

1 reference

Europe PubMed Central

31 October 2017

publication date

14 July 2010

1 reference

Europe PubMed Central

31 October 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

31 October 2017

21

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Europe PubMed Central

31 October 2017

17

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Europe PubMed Central

31 October 2017

2975-2986

1 reference

Europe PubMed Central

31 October 2017

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Regulation of hepatic lipogenesis by the transcription factor XBP1

1 reference

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28 May 2018

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Transcriptional regulation of peroxisome proliferator-activated receptors and liver X receptors.

1 reference

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28 May 2018

The blind men 'see' the elephant-the many faces of fatty liver disease

1 reference

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28 May 2018

Nonalcoholic fatty liver disease and mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

1 reference

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28 May 2018

PPARalpha and dyslipidemia

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28 May 2018

The role of p58IPK in protecting the stressed endoplasmic reticulum

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28 May 2018

Signal integration in the endoplasmic reticulum unfolded protein response

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28 May 2018

Diversity of endotoxin and its impact on pathogenesis

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28 May 2018

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload

1 reference

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28 May 2018

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

1 reference

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28 May 2018

Molecular chaperones and protein quality control

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28 May 2018

Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation

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28 May 2018

Lipid droplets: a unified view of a dynamic organelle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Mouse models in non-alcoholic fatty liver disease and steatohepatitis research.

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28 May 2018

Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis.

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28 May 2018

Protein synthesis upon acute nutrient restriction relies on proteasome function

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28 May 2018

Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans.

1 reference

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28 May 2018

The mammalian unfolded protein response

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28 May 2018

Nonalcoholic fatty liver disease

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28 May 2018

Mechanisms of non-alcoholic steatohepatitis

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28 May 2018

Molecular mediators of hepatic steatosis and liver injury

1 reference

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28 May 2018

Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

HSP47 as a collagen-specific molecular chaperone: function and expression in normal mouse development

1 reference

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28 May 2018

Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant

1 reference

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28 May 2018

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Nonalcoholic steatohepatitis: what we know in the new millennium

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28 May 2018

Pathogenesis of steatohepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

The surface of lipid droplets is a phospholipid monolayer with a unique Fatty Acid composition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins

1 reference

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Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

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28 May 2018

Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways

1 reference

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28 May 2018

Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response

1 reference

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28 May 2018

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

1 reference

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28 May 2018

Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response

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28 May 2018

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Tripartite management of unfolded proteins in the endoplasmic reticulum

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28 May 2018

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

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28 May 2018

HRD gene dependence of endoplasmic reticulum-associated degradation

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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Protein disulfide isomerase: the multifunctional redox chaperone of the endoplasmic reticulum

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28 May 2018

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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Steatohepatitis: a tale of two "hits"?

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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

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Developmental changes of synapsin I subcellular localization in rat cerebellar neurons.

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Degradation of newly synthesized apolipoprotein B-100 in a pre-Golgi compartment

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CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

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https://pubmed.ncbi.nlm.nih.gov/20631254

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CuZn-SOD deficiency causes ApoB degradation and induces hepatic lipid accumulation by impaired lipoprotein secretion in mice

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based on heuristic

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Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E09-02-0133

1 reference

Europe PubMed Central

31 October 2017

1 reference

Europe PubMed Central

31 October 2017

1 reference

Europe PubMed Central

31 October 2017

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