Regulation of the p300 HAT domain via a novel activation loop. (Q42458138)

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25 December 2019

title

Regulation of the p300 HAT domain via a novel activation loop (English)

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11

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Vittorio Sartorelli

12

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25 December 2019

author name string

Paul R Thompson

1

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Dongxia Wang

2

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Ling Wang

3

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Marcella Fulco

4

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Natalia Pediconi

5

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Dianzheng Zhang

6

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Woojin An

7

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Qingyuan Ge

8

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Robert G Roeder

9

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Jiemin Wong

10

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Robert J Cotter

13

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Philip A Cole

14

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publication date

7 March 2004

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Nature Structural & Molecular Biology

25 December 2019

published in

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volume

11

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issue

4

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page(s)

308-315

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https://scigraph.springernature.com/pub.10.1038/nsmb740

25 December 2019

exact match

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cites work

The transcriptional coactivators p300 and CBP are histone acetyltransferases

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The CBP co-activator is a histone acetyltransferase

31 March 2020

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Mutations truncating the EP300 acetylase in human cancers

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The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

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MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.

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Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders

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The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity

31 March 2020

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p300 Transcriptional Repression Is Mediated by SUMO Modification

31 March 2020

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Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice

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Control of CBP co-activating activity by arginine methylation

31 March 2020

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Analysis with specific polyclonal antiserum indicates that the E1A-associated 300-kDa product is a stable nuclear phosphoprotein that undergoes cell cycle phase-specific modification

31 March 2020

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Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

31 March 2020

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Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A

31 March 2020

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Transcriptional coactivator protein p300. Kinetic characterization of its histone acetyltransferase activity

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Histone acetyltransferases

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31 March 2020

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Plant orthologs of p300/CBP: conservation of a core domain in metazoan p300/CBP acetyltransferase-related proteins

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DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.

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The human proliferating Cell nuclear antigen regulates transcriptional coactivator p300 activity and promotes transcriptional repression.

31 March 2020

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Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein

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High-throughput screening for identification of small molecule inhibitors of histone acetyltransferases using scintillating microplates (FlashPlate).

31 March 2020

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HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF.

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The conformational plasticity of protein kinases

31 March 2020

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Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?

31 March 2020

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The bromodomain: a chromatin-targeting module?

31 March 2020

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Reassessment of Ellman's reagent

31 March 2020

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

31 March 2020

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A role for cofactor-cofactor and cofactor-histone interactions in targeting p300, SWI/SNF and Mediator for transcription

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB740

1 reference

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25 December 2019

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