Indinavir impairs protein synthesis and phosphorylations of MAPKs in mouse C2C12 myocytes (Q42464012)

1 November 2017

Indinavir impairs protein synthesis and phosphorylations of MAPKs in mouse C2C12 myocytes (English)

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1 November 2017

1 reference

Ly Q Hong-Brown

1

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PubMed ID

15229102

1 November 2017

C Randell Brown

series ordinal

2

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PubMed ID

15229102

1 November 2017

Charles H Lang

series ordinal

3

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1 November 2017

30 June 2004

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American Journal of Physiology - Cell Physiology

1 November 2017

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1 November 2017

287

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1 November 2017

5

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1 November 2017

C1482-92

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 November 2017

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The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance

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A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors

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The HIV protease inhibitor Indinavir inhibits cell-cycle progression in vitro in lymphocytes of HIV-infected and uninfected individuals

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

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Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

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Ribosomal S6 kinase signaling and the control of translation

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A protein kinase from Xenopus eggs specific for ribosomal protein S6.

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Characterization of ribosomal S6 protein kinase p90rsk during meiotic maturation and fertilization in pig oocytes: mitogen-activated protein kinase-associated activation and localization

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Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

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MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

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Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

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The metabolic toxicities of antiretroviral therapy

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Alcohol impairs protein synthesis and degradation in cultured skeletal muscle cells

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c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

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Initial antiretroviral regimens

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Alcohol impairs insulin and IGF-I stimulation of S6K1 but not 4E-BP1 in skeletal muscle

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Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway

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Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory and rapamycin sensitivity domains

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MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

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Phosphorylation of eukaryotic initiation factor 4E (eIF4E) at Ser209 is not required for protein synthesis in vitro and in vivo

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Involvement of stress-activated protein kinase and p38/RK mitogen-activated protein kinase signaling pathways in the enhanced phosphorylation of initiation factor 4E in NIH 3T3 cells

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The mechanism of insulin resistance caused by HIV protease inhibitor therapy.

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Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

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Phosphorylation and activation of p70s6k by PDK1

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The modular phosphorylation and activation of p70s6k.

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Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

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The HIV protease inhibitor saquinavir impairs lipid metabolism and glucose transport in cultured adipocytes

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Thrombin- and factor Xa-induced DNA synthesis is mediated by transactivation of fibroblast growth factor receptor-1 in human vascular smooth muscle cells

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Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site

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Impact of protease inhibitors and other antiretroviral treatments on acquired immunodeficiency syndrome survival in San Francisco, California, 1987-1996.

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Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes

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Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes

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The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways

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Indinavir alters sterol and fatty acid homeostatic mechanisms in primary rat hepatocytes by increasing levels of activated sterol regulatory element-binding proteins and decreasing cholesterol 7alpha-hydroxylase mRNA levels

21 January 2018

1 reference

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10.1152/AJPCELL.00038.2004

21 January 2018

Identifiers

DOI

1 reference

1 November 2017

1 reference

PubMed ID

15229102