Free radical modulation of insulin release in INS-1 cells exposed to alloxan (Q42468349)

1 November 2017

Free radical modulation of insulin release in INS-1 cells exposed to alloxan (English)

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1 November 2017

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Janjic D

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1 November 2017

Maechler P

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1 November 2017

Sekine N

3

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1 November 2017

Bartley C

4

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1 November 2017

Annen AS

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1 November 2017

Wolheim CB

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1 November 2017

language of work or name

English

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publication date

1 March 1999

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1 November 2017

Biochemical Pharmacology

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1 November 2017

57

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1 November 2017

6

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1 November 2017

639-648

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Alloxan: history and mechanism of action

1 November 2017

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Superoxide dismutase is a prophylactic against alloxan diabetes

7 January 2021

1 reference

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Determinants of the selective toxicity of alloxan to the pancreatic B cell

7 January 2021

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Chemiluminescence as an Index of Drug-induced Free Radical Production in Pancreatic Islets

7 January 2021

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Mechanisms of streptozotocin- and alloxan-induced damage in rat B cells

7 January 2021

1 reference

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Structural requirements of alloxan and ninhydrin for glucokinase inhibition and of glucose for protection against inhibition

7 January 2021

1 reference

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Alloxan and ninhydrin inhibition of hexokinase from pancreatic islets and tumoural insulin-secreting cells

7 January 2021

1 reference

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Islet cell metabolism is reflected by the MTT (tetrazolium) colorimetric assay

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Postreceptor signalling of growth hormone and prolactin and their effects in the differentiated insulin-secreting cell line, INS-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Auto-oxidation of dialuric acid, divicine and isouramil. Superoxide dependent and independent mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Glutathione-mediated redox cycling of alloxan. Mechanisms of superoxide dismutase inhibition and of metal-catalyzed OH. formation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Thioredoxin and thioredoxin reductase in pancreatic islets may participate in diabetogenic free-radical production

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Effect of extracellularly generated free radicals on the plasma membrane permeability of isolated pancreatic B-cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Alloxan effects on mitochondria: study of oxygen consumption, fluxes of Mg2+, Ca2+, K+ and adenine nucleotides, membrane potential and volume change in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Alloxan cytotoxicity is highly potentiated by plasma membrane- and lysosomal-associated iron--a study on a model system of cultured J-774 cells

7 January 2021

1 reference

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In vivo modulation of total and mitochondrial glutathione in rat liver. Depletion by phorone and rescue by N-acetylcysteine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Effects of alloxan and ninhydrin on mitochondrial Ca2+ transport

7 January 2021

1 reference

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CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Pancreatic B cells possess defense mechanisms against cell-specific toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Functional restoration of cultured mouse pancreatic islets after in vitro exposure to alloxan

7 January 2021

1 reference

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Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury

7 January 2021

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Comparison of superoxide dismutase activities in isolated rat and guinea pig islets of Langerhans

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Resistance to alloxan of tumoral insulin-producing cells

7 January 2021

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Studies on the chemical and immunological destruction of insulin-secreting islet cell tumours.

7 January 2021

1 reference

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Alloxan-induced alteration of insulin release, rubidium efflux and glucose metabolism in rat islets stimulated by various secretagogues

7 January 2021

1 reference

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Alloxan Stimulation and Inhibition of Insulin Release from Isolated Rat Islets of Langerhans

7 January 2021

1 reference

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Glucose and 3-0-Methylglucose Protection Against Alloxan Poisoning of Pancreatic Alpha and Beta Cells

7 January 2021

1 reference

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The bioelectrical properties of pancreatic islet cells: effects of diabetogenic agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Disappearance of glucose-induced oscillations of cytoplasmic Ca2+ in pancreatic beta-cells exposed to streptozotocin or alloxan

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Activation of a novel non-selective cation channel by alloxan and H2O2 in the rat insulin-secreting cell line CRI-G1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Involvement of ATP-sensitive K+ channels in free radical-mediated inhibition of insulin secretion in rat pancreatic beta-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900346-3

10.1016/S0006-2952(98)00346-3

7 January 2021

Identifiers

DOI

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1 November 2017

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