Hyperactivation of mitogen-activated protein kinase increases phospho-tau immunoreactivity within human neuroblastoma: additive and synergistic influence of alteration of additional kinase activities (Q42469160)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Hyperactivation of mitogen-activated protein kinase increases phospho-tau immunoreactivity within human neuroblastoma: additive and synergistic influence of alteration of additional kinase activities	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

1 November 2017

Hyperactivation of mitogen-activated protein kinase increases phospho-tau immunoreactivity within human neuroblastoma: additive and synergistic influence of alteration of additional kinase activities (English)

1 reference

Europe PubMed Central

1 November 2017

1 reference

based on heuristic

inferred from title

author name string

F J Ekinci

1

1 reference

Europe PubMed Central

1 November 2017

T B Shea

2

1 reference

Europe PubMed Central

1 November 2017

publication date

1 April 1999

1 reference

Europe PubMed Central

1 November 2017

Cellular and Molecular Neurobiology

1 reference

Europe PubMed Central

1 November 2017

19

1 reference

Europe PubMed Central

1 November 2017

2

1 reference

Europe PubMed Central

1 November 2017

249-260

1 reference

Europe PubMed Central

1 November 2017

https://scigraph.springernature.com/pub.10.1023/a:1006981228331

0 references

Altered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for Alzheimer's disease and Lewy body dementias

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of microtubule-associated protein tau: identification of the site for Ca2(+)-calmodulin dependent kinase and relationship with tau phosphorylation in Alzheimer tangles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid Alzheimer-like phosphorylation of tau by the synergistic actions of non-proline-dependent protein kinases and GSK-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular messengers in the generation and degeneration of hippocampal neuroarchitecture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubule-associated protein tau is hyperphosphorylated during mitosis in the human neuroblastoma cell line SH-SY5Y.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+-dependent and Ca2+-independent protein kinase C changes in the brain of patients with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p44mpk MAP kinase induces Alzheimer type alterations in tau function and in primary hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disturbances in signal transduction mechanisms in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau domains, phosphorylation, and interactions with microtubules.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of GSK-3-catalyzed phosphorylation of microtubule-associated protein tau by non-proline-dependent protein kinases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid and ionophore A23187 evoke tau hyperphosphorylation by distinct intracellular pathways: differential involvement of the calpain/protein kinase C system

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of neurite outgrowth following calpain inhibition is mediated by protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the involvement of protein kinase C in neurodegenerative changes in cultured human cortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of mitogen-activated protein kinase activation by protein kinases A and C in a cell-free system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calpain-mediated proteolysis of microtubule-associated protein 2 (MAP-2) is inhibited by phosphorylation by cAMP-dependent protein kinase, but not by Ca2+/calmodulin-dependent protein kinase II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and differential distribution of the three major human protein kinase C isozymes (PKC alpha, PKC beta, and PKC gamma) of the central nervous system in normal and Alzheimer's disease brains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C alteration is an early biochemical marker in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiology and pathology of tau protein kinases in relation to Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C activity and protein levels in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormally phosphorylated tau in SY5Y human neuroblastoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of protein phosphatases (PP-1, PP-2A, PP-2B and PTP-1B) and protein kinases (MAP kinase and P34cdc2) in the hippocampus of patients with Alzheimer disease and normal aged individuals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction mechanisms in Alzheimer disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphosphorylation of the cytoskeletal protein Tau by the MAP-kinase PK40erk2: regulation by prior phosphorylation with cAMP-dependent protein kinase A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective protein kinase C alpha leads to impaired secretion of soluble beta-amyloid precursor protein from Alzheimer's disease fibroblasts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant protein kinase C cascades in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipids alter tau conformation, phosphorylation, proteolysis, and association with microtubules: implication for tau function under normal and degenerative conditions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylated tau epitope of Alzheimer's disease is coupled to axon development in the avian central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphosphorylation of human TAU by brain kinase PK40erk beyond phosphorylation by cAMP-dependent PKA: relation to Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium influx into human neuroblastoma cells induces ALZ-50 immunoreactivity: involvement of calpain-mediated hydrolysis of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of the Swedish familial Alzheimer's disease mutant phenotype in cultured cells treated with phorbol 12,13-dibutyrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphosphorylation of Tau and filopodial retraction following microinjection of protein kinase C catalytic subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The order of exposure of tau to signal transduction kinases alters the generation of "AD-like" phosphoepitopes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosol protein kinase C downregulation in fibroblasts from Alzheimer's disease patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cdc2-related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of tau proteins to a state like that in Alzheimer's brain is catalyzed by a calcium/calmodulin-dependent kinase and modulated by phospholipids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuated protein kinase C activity and translocation in Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proline-directed kinase systems in Alzheimer's disease pathology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation events mediated by protein kinase C alpha and epsilon participate in regulation of tau steady-state levels and generation of certain "Alzheimer-like" phospho-epitopes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium influx recruits an additional class of kinases to hyperphosphorylate tau

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of MAP kinase by v-raf transformation of fibroblasts fails to induce hyperphosphorylation of transfected tau.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau protein kinase II is involved in the regulation of the normal phosphorylation state of tau protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10081608

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1006981228331

1 reference

Europe PubMed Central

1 November 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

1 November 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q42469160&oldid=1958565247"