BRCA1 negatively regulates formation of autophagic vacuoles in MCF-7 breast cancer cells (Q42473747)

1 November 2017

BRCA1 negatively regulates formation of autophagic vacuoles in MCF-7 breast cancer cells (English)

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1 November 2017

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Juan M Esteve

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1 November 2017

María Eugenia Armengod

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2

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1 November 2017

Erwin Knecht

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3

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1 November 2017

language of work or name

English

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publication date

1 July 2010

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Experimental Cell Research

1 November 2017

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1 November 2017

316

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1 November 2017

16

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1 November 2017

2618-2629

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Intracellular protein degradation in mammalian cells: recent developments

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In search of an "autophagomometer".

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Regulation of various proteolytic pathways by insulin and amino acids in human fibroblasts

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Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B.

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Vanadate-induced cell death is dissociated from H2O2 generation.

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BRCA1 mRNA expression levels as an indicator of chemoresistance in lung cancer

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Autophagy in health and disease: a double-edged sword

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Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

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The lysosomotropic agent monodansylcadaverine also acts as a solvent polarity probe

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Rab7 is required for the normal progression of the autophagic pathway in mammalian cells

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Growth retardation and tumour inhibition by BRCA1.

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Maturation of autophagic vacuoles in Mammalian cells

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Low concentrations of diindolylmethane, a metabolite of indole-3-carbinol, protect against oxidative stress in a BRCA1-dependent manner

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Phosphorylated BRCA1 is predominantly located in the nucleus and mitochondria

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Mitochondrial localization, ELK-1 transcriptional regulation and growth inhibitory functions of BRCA1, BRCA1a, and BRCA1b proteins

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The paradox of autophagy and its implication in cancer etiology and therapy

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The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras.

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Regulation of BRCA1 by protein degradation

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Role of BRCA1 in heat shock response

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ROS, mitochondria and the regulation of autophagy

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10.1016/J.YEXCR.2010.06.019

7 January 2021

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DOI

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1 November 2017

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