Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils (Q42474134)

1 November 2017

Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils (English)

1 reference

1 November 2017

Zachary T Kneass

1

1 reference

PubMed ID

15703172

1 November 2017

Richard B Marchase

series ordinal

2

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PubMed ID

15703172

1 November 2017

language of work or name

English

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publication date

9 February 2005

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Journal of Biological Chemistry

1 November 2017

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1 November 2017

280

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1 November 2017

15

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1 November 2017

14579-14585

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Glycosylation of nucleocytoplasmic proteins: signal transduction and O-GlcNAc

1 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

O-GlcNAc: a regulatory post-translational modification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Dynamic interplay between O-glycosylation and O-phosphorylation of nucleocytoplasmic proteins: a new paradigm for metabolic control of signal transduction and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Lymphocyte activation induces rapid changes in nuclear and cytoplasmic glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Glycosylation in the nucleus and cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

O-GlcNAc turns twenty: functional implications for post-translational modification of nuclear and cytosolic proteins with a sugar

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

The transcription factor PDX-1 is post-translationally modified by O-linked N-acetylglucosamine and this modification is correlated with its DNA binding activity and insulin secretion in min6 beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

YY1 is regulated by O-linked N-acetylglucosaminylation (O-glcNAcylation).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

O-GlcNAc modification is an endogenous inhibitor of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Neutrophils exhibit rapid agonist-induced increases in protein-associated O-GlcNAc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Characterization of the MEK5-ERK5 module in human neutrophils and its relationship to ERK1/ERK2 in the chemotactic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Potential role of IL-8, platelet-activating factor and TNF-alpha in the sequestration of neutrophils in the lung: effects on neutrophil deformability, adhesion receptor expression, and chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Propofol inhibits FMLP-stimulated phosphorylation of p42 mitogen-activated protein kinase and chemotaxis in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

CD38 cleavage in fMLP- and IL-8-induced chemotaxis is dependent on p38 MAP kinase but independent of p44/42 MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

MAPK-activated protein kinase-2 participates in p38 MAPK-dependent and ERK-dependent functions in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Abnormal migration phenotype of mitogen-activated protein kinase-activated protein kinase 2-/- neutrophils in Zigmond chambers containing formyl-methionyl-leucyl-phenylalanine gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

A requirement of MAPKAPK2 in the uropod localization of PTEN during FMLP-induced neutrophil chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

LSP1 is the major substrate for mitogen-activated protein kinase-activated protein kinase 2 in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Modulation of Mac-1 (CD11b/CD18)-mediated adhesion by the leukocyte-specific protein 1 is key to its role in neutrophil polarization and chemotaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

HSP27 regulates fibroblast adhesion, motility, and matrix contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Control of actin dynamics by p38 MAP kinase - Hsp27 distribution in the lamellipodium of smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

N-acetylglucosaminono-1,5-lactone oxime and the corresponding (phenylcarbamoyl)oxime. Novel and potent inhibitors of beta-N-acetylglucosaminidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-beta-N-acetylglucosaminidase inhibitor O-(2-acetamido-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Short-range RNA-RNA crosslinking methods to determine rRNA structure and interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Cytosolic O-GlcNAc accumulation is not involved in beta-cell death in HIT-T15 or Min6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Rho and Rac take center stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Differential activation of the Rac pathway by Ha-Ras and K-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Ras and Rho GTPases: a family reunion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Role of the glucosamine pathway in fat-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Beta-amyloid precursor protein is modified with O-linked N-acetylglucosamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Characterization of RAC3, a novel member of the Rho family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

High glucose-induced upregulation of osteopontin is mediated via Rho/Rho kinase pathway in cultured rat aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Chemotactic peptide N-formyl-met-leu-phe activation of p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase-2 in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-ce

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

P38 mitogen-activated protein kinase mediates hexosamine-induced TGFbeta1 mRNA expression in human mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414066200

21 January 2018

Identifiers

DOI

10.1074/JBC.M414066200

1 reference

1 November 2017

1 reference

PubMed ID

15703172