Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition (Q42477784)

1 November 2017

title

Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition (English)

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Manfred Heckmann

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Anna-Leena Sirén

object named as

Anna-Leena Sirén

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Klaus Viktor Toyka

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object named as

Klaus V Toyka

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Claudia Sommer

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Christian Geis

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Andreas Weishaupt

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Benedikt Grünewald

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Carsten Wessig

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Thomas Wultsch

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Andreas Reif

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Nadiya Byts

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Marcus Beck

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Sibylle Jablonka

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Wernher Fouquet

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Manfred Gerlach

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Hans-Michael Meinck

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Stephan J Sigrist

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language of work or name

English

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publication date

30 September 2010

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volume

133

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issue

11

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page(s)

3166-3180

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Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica

1 November 2017

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The clinical spectrum of anti-GAD antibody-positive patients with stiff-person syndrome

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A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals

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Autoimmunity in stiff-Man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161

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Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice

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PHARMACOLOGICAL STUDIES ON PRESYNAPTIC INHIBITION.

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Amphiphysin is a component of clathrin coats formed during synaptic vesicle recycling at the lamprey giant synapse

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A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis

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Autoantibodies to a 128-kd synaptic protein in three women with the stiff-man syndrome and breast cancer

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Passive transfer of Lambert-Eaton myasthenic syndrome with IgG from man to mouse depletes the presynaptic membrane active zones

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The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence

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Cell- and stimulus-dependent heterogeneity of synaptic vesicle endocytic recycling mechanisms revealed by studies of dynamin 1-null neurons

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Spinal reflexes, mechanisms and concepts: from Eccles to Lundberg and beyond

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Bruchpilot promotes active zone assembly, Ca2+ channel clustering, and vesicle release

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Kinetics and regulation of fast endocytosis at hippocampal synapses

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The journey of tetanus and botulinum neurotoxins in neurons

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Effect of spinal cord injury severity on alterations of the H-reflex

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IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel

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In vitro studies of prolonged synaptic depression in the neonatal rat spinal cord

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Autoimmunity due to molecular mimicry as a cause of neurological disease

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The stiff-man syndrome: new pathophysiological aspects from abnormal exteroceptive reflexes and the response to clomipramine, clonidine, and tizanidine

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Stiff man syndrome and related conditions

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Autoimmunity to GABAA-receptor-associated protein in stiff-person syndrome

21 January 2018

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Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis

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Mutations in the alpha 1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia

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Synaptic vesicle endocytosis impaired by disruption of dynamin-SH3 domain interactions

21 January 2018

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Paraneoplastic cerebellar ataxia due to autoantibodies against a glutamate receptor

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Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus

21 January 2018

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Paraneoplastic stiff-person syndrome: passive transfer to rats by means of IgG antibodies to amphiphysin

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Disinhibition opens the gate to pathological pain signaling in superficial neurokinin 1 receptor-expressing neurons in rat spinal cord.

21 January 2018

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Autoantibodies, neurotoxins and the nervous system

21 January 2018

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Neuropathology and binding studies in anti-amphiphysin-associated stiff-person syndrome

21 January 2018

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The amphiphysin family of proteins and their role in endocytosis at the synapse

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Chronic catheterization of the spinal subarachnoid space

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21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWQ253

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1 November 2017

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