Hydrophobic residues Phe751 and Leu753 are essential for STAT5 transcriptional activity (Q42485987)

1 November 2017

title

Hydrophobic residues Phe751 and Leu753 are essential for STAT5 transcriptional activity (English)

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1 November 2017

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Callus BA

1

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1 November 2017

Mathey-Prevot B

series ordinal

2

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1 November 2017

language of work or name

English

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publication date

1 June 2000

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Journal of Biological Chemistry

1 November 2017

published in

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1 November 2017

volume

275

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1 November 2017

issue

22

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1 November 2017

page(s)

16954-16962

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Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

1 November 2017

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Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

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Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway

21 January 2018

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Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein

21 January 2018

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A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

21 January 2018

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Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

21 January 2018

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Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

21 January 2018

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Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1

21 January 2018

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A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain

21 January 2018

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Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

21 January 2018

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Three-dimensional structure of the Stat3beta homodimer bound to DNA

21 January 2018

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Amino-terminal signal transducer and activator of transcription (STAT) domains regulate nuclear translocation and STAT deactivation.

21 January 2018

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Structure of the amino-terminal protein interaction domain of STAT-4

21 January 2018

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Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1.

21 January 2018

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Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

21 January 2018

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Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling

21 January 2018

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Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.

21 January 2018

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Naturally occurring dominant negative variants of Stat5.

21 January 2018

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Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation

21 January 2018

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21 January 2018

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Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha

21 January 2018

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Stat protein transactivation domains recruit p300/CBP through widely divergent sequences

21 January 2018

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p300/CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in the Stat5-mediated suppression of the glucocorticoid response

21 January 2018

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p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6.

21 January 2018

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Rapid selection of tetracycline-controlled inducible cell lines using a green fluorescent-transactivator fusion protein

21 January 2018

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Cooperation between core binding factor and adjacent promoter elements contributes to the tissue-specific expression of interleukin-3.

21 January 2018

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Locating transcribed and non-transcribed rDNA spacer sequences within the nucleolus by in situ hybridization and immunoelectron microscopy

21 January 2018

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Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene

21 January 2018

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Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

21 January 2018

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

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A new class of yeast transcriptional activators

21 January 2018

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Mutants of GAL4 protein altered in an activation function

21 January 2018

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Mutations that increase the activity of a transcriptional activator in yeast and mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909976199

Pattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activator

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909976199

Specific inhibition of Stat3 signal transduction by PIAS3

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909976199

Inhibition of Stat1-mediated gene activation by PIAS1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909976199

Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909976199

Extensive mutagenesis of a transcriptional activation domain identifies single hydrophobic and acidic amino acids important for activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909976199

Crystal structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909976199

The acidic activation domains of the GCN4 and GAL4 proteins are not alpha helical but form beta sheets

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909976199

Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor

21 January 2018

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Acid blobs and negative noodles

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909976199

Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909976199

Erythropoietin receptor activation by a ligand-induced conformation change

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909976199

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909976199

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909976199

Pre-bending of a promoter sequence enhances affinity for the TATA-binding factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909976199

Critical structural elements of the VP16 transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909976199

Role of acidic and phosphorylated residues in gene activation by the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909976199

Genetic evidence that an activation domain of GAL4 does not require acidity and may form a beta sheet

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909976199

21 January 2018

Identifiers

DOI

10.1074/JBC.M909976199

1 reference

1 November 2017

1 reference