Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane. (Q42487983)

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31 January 2020

title

Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane (English)

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31 January 2020

author

Constance Lay-Lay Saw

1

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31 January 2020

author name string

Mou-Tuan Huang

2

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31 January 2020

Yue Liu

3

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31 January 2020

Tin Oo Khor

4

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31 January 2020

Allan H Conney

5

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31 January 2020

Ah-Ng Kong

6

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publication date

28 December 2010

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31 January 2020

published in

Molecular Carcinogenesis

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31 January 2020

volume

50

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31 January 2020

issue

6

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31 January 2020

page(s)

479-486

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Sunlight and the onset of skin cancer

31 January 2020

cites work

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Cutaneous squamous-cell carcinoma

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The epidemiology of skin cancer

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Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2.

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Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion.

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Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts

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Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway

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Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles.

21 January 2018

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The significance of Nrf2 pathway in (photo)-oxidative stress response in melanocytes and keratinocytes of the human epidermis

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Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing

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Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress

21 January 2018

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Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling comp

21 January 2018

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Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis

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Attenuation of UVB-induced sunburn reaction and oxidative DNA damage with no alterations in UVB-induced skin carcinogenesis in Nrf2 gene-deficient mice

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Low and high dose UVB regulation of transcription factor NF-E2-related factor 2.

21 January 2018

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8-Oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis

21 January 2018

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Role of Nrf2 in suppressing LPS-induced inflammation in mouse peritoneal macrophages by polyunsaturated fatty acids docosahexaenoic acid and eicosapentaenoic acid

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Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis.

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Differential regulation of TNF-alpha, IL-6 and IL-10 in UVB-irradiated human keratinocytes via cyclic AMP/protein kinase A pathway

21 January 2018

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Sunburn and p53 in the onset of skin cancer

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