The Agrin/MuSK signaling pathway is spatially segregated from the neuregulin/ErbB receptor signaling pathway at the neuromuscular junction. (Q42496754)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11102484%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

The Agrin/MuSK signaling pathway is spatially segregated from the neuregulin/ErbB receptor signaling pathway at the neuromuscular junction (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11102484%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

main subject

neuromuscular junction

1 reference

2

Fischbach GD

1 reference

PubMed publication ID

1 November 2017

J C Trinidad

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11102484%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

G D Fischbach

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11102484%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

J B Cohen

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11102484%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

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publication date

1 December 2000

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11102484%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

published in

Journal of Neuroscience

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2 November 2019

volume

20

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2 November 2019

issue

23

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2 November 2019

page(s)

8762-8770

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The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

2 November 2019

cites work

1 reference

12 December 2020

Different distributions of dystrophin and related proteins at nerve-muscle junctions

1 reference

12 December 2020

Agrin acts via a MuSK receptor complex

1 reference

12 December 2020

Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold

1 reference

12 December 2020

Regulation of the acetylcholine receptor epsilon subunit gene by recombinant ARIA: an in vitro model for transynaptic gene regulation

1 reference

12 December 2020

Nerve terminal withdrawal from rat neuromuscular junctions induced by neuregulin and Schwann cells

1 reference

12 December 2020

ACh receptor-rich membrane domains organized in fibroblasts by recombinant 43-kildalton protein

1 reference

12 December 2020

beta-Spectrin is colocalized with both voltage-gated sodium channels and ankyrinG at the adult rat neuromuscular junction

1 reference

12 December 2020

Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development.

1 reference

12 December 2020

ARIA is concentrated in the synaptic basal lamina of the developing chick neuromuscular junction

1 reference

12 December 2020

The postsynaptic 43k protein clusters muscle nicotinic acetylcholine receptors in xenopus oocytes

1 reference

12 December 2020

Agrin-induced postsynaptic-like apparatus in skeletal muscle fibers in vivo

1 reference

12 December 2020

Association of muscle-specific kinase MuSK with the acetylcholine receptor in mammalian muscle.

1 reference

12 December 2020

Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction

1 reference

12 December 2020

Heregulin-stimulated acetylcholine receptor gene expression in muscle: requirement for MAP kinase and evidence for a parallel inhibitory pathway independent of electrical activity

1 reference

12 December 2020

ARIA is concentrated in nerve terminals at neuromuscular junctions and at other synapses

1 reference

12 December 2020

The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses

1 reference

12 December 2020

ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms

1 reference

12 December 2020

Identification of a neuregulin and protein-tyrosine phosphatase response element in the nicotinic acetylcholine receptor epsilon subunit gene: regulatory role of an Rts transcription factor

1 reference

12 December 2020

Essential roles of c-JUN and c-JUN N-terminal kinase (JNK) in neuregulin-increased expression of the acetylcholine receptor epsilon-subunit

1 reference

12 December 2020

Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice

1 reference

12 December 2020

Development of the vertebrate neuromuscular junction

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12 December 2020

Spatial relationships of utrophin, dystrophin, beta-dystroglycan and beta-spectrin to acetylcholine receptor clusters during postnatal maturation of the rat neuromuscular junction.

1 reference

12 December 2020

Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

1 reference

12 December 2020

Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins

1 reference

12 December 2020

Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers

1 reference

12 December 2020

Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations.

1 reference

12 December 2020

ARIA: a neuromuscular junction neuregulin

1 reference

12 December 2020

An immunological approach reveals biological differences between the two NDF/heregulin receptors, ErbB-3 and ErbB-4.

1 reference

12 December 2020

The Role of Agrin in Synapse Formation

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12 December 2020

Synapse-specific and neuregulin-induced transcription require an ets site that binds GABPalpha/GABPbeta

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12 December 2020

Sequential roles of agrin, MuSK and rapsyn during neuromuscular junction formation

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12 December 2020

1 reference

12 December 2020

RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubes

1 reference

12 December 2020

ErbB3 and ErbB2/neu mediate the effect of heregulin on acetylcholine receptor gene expression in muscle: differential expression at the endplate.

1 reference

12 December 2020

Constitutively active MuSK is clustered in the absence of agrin and induces ectopic postsynaptic-like membranes in skeletal muscle fibers.

1 reference

12 December 2020

Synapse-Associated Expression of an Acetylcholine Receptor-Inducing Protein, ARIA/Heregulin, and Its Putative Receptors, ErbB2 and ErbB3, in Developing Mammalian Muscle

1 reference

12 December 2020

Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells.

1 reference

12 December 2020

Stimulation of myogenic differentiation by a neuregulin, glial growth factor 2. Are neuregulins the long-sought muscle trophic factors secreted by nerves?

1 reference

12 December 2020

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

1 reference

12 December 2020

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice.

1 reference

12 December 2020

Activation of ErbB2 during wallerian degeneration of sciatic nerve

1 reference

12 December 2020

Expression patterns of transmembrane and released forms of neuregulin during spinal cord and neuromuscular synapse development.

1 reference

12 December 2020

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor

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12 December 2020

Neuregulin stimulates myogenic differentiation in an autocrine manner

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12 December 2020

Acetylcholine receptor-inducing activity stimulates expression of the epsilon-subunit gene of the muscle acetylcholine receptor

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12 December 2020

Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships

1 reference

12 December 2020

Developmental regulation of highly active alternatively spliced forms of agrin

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12 December 2020

Defective neuromuscular synaptogenesis in agrin-deficient mutant mice

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12 December 2020

Mechanism of nicotinic acetylcholine receptor cluster formation by rapsyn

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12 December 2020

Distribution of Na+ channels and ankyrin in neuromuscular junctions is complementary to that of acetylcholine receptors and the 43 kd protein

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12 December 2020

Axon withdrawal during synapse elimination at the neuromuscular junction is accompanied by disassembly of the postsynaptic specialization and withdrawal of Schwann cell processes.

1 reference

12 December 2020

Alternative intracellular routing of ErbB receptors may determine signaling potency

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12 December 2020

Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapses

1 reference

12 December 2020

Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3.

1 reference

12 December 2020

Syntrophin isoforms at the neuromuscular junction: developmental time course and differential localization.

1 reference

12 December 2020

Agrin can mediate acetylcholine receptor gene expression in muscle by aggregation of muscle-derived neuregulins

1 reference

12 December 2020

Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration

1 reference

12 December 2020

10.1523/JNEUROSCI.20-23-08762.2000

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11102484%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11102484%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

11102484

1 reference