Releasing the block: setting differentiation free with mutant IDH inhibitors. (Q42498717)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23680144%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Releasing the block: setting differentiation free with mutant IDH inhibitors (English)

1 reference

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1 March 2020

2

1 reference

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1 March 2020

author name string

Christopher J Pirozzi

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23680144%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Hai Yan

series ordinal

3

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1 March 2020

publication date

1 May 2013

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1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23680144%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

23

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1 March 2020

issue

5

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1 March 2020

page(s)

570-572

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Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation

1 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

Mutant IDH1 is required for IDH1 mutated tumor cell growth.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

IDH mutation impairs histone demethylation and results in a block to cell differentiation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

IDH1 and IDH2 mutations in gliomas

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465106

10.1016/J.CCR.2013.04.024

28 May 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23680144%20AND%20SRC:MED&resulttype=core&format=json

release_243llouzcbhjvniriifxfx34wi

1 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/243llouzcbhjvniriifxfx34wi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23680144%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

23680144

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23680144%20AND%20SRC:MED&resulttype=core&format=json