Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes (Q42503051)

1 November 2017

Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes (English)

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1 November 2017

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R Hernandez

1

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1 November 2017

T Teruel

series ordinal

2

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1 November 2017

M Lorenzo

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3

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1 November 2017

language of work or name

English

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publication date

1 April 2001

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1 November 2017

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1 November 2017

494

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1 November 2017

225-231

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1 November 2017

3

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Insulin-like growth factor I and insulin induce adipogenic-related gene expression in fetal brown adipocyte primary cultures.

1 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Insulin/IGF-I rescues immortalized brown adipocytes from apoptosis down-regulating Bcl-xS expression, in a PI 3-kinase- and map kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Signaling pathways in insulin action: molecular targets of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Akt mediates insulin rescue from apoptosis in brown adipocytes: effect of ceramide

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Decreased expression of the insulin-responsive glucose transporter in diabetes and fasting.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Regulation of glucose transporter messenger RNA in insulin-deficient states

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Insulin down-regulates expression of the insulin-responsive glucose transporter (GLUT4) gene: effects on transcription and mRNA turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Insulin and insulin-like growth factor 1 antagonize the stimulation of ob gene expression by dexamethasone in cultured rat adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Regulation of glucose transporters in cultured rat adipocytes: synergistic effect of insulin and dexamethasone on GLUT4 gene expression through promoter activation.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Identification of a novel gene encoding an insulin-responsive glucose transporter protein

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Cyclic adenosine 3',5'-monophosphate regulates GLUT4 and GLUT1 glucose transporter expression and stimulates transcriptional activity of the GLUT1 promoter in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Insulin-stimulated GLUT4 translocation is mediated by a divergent intracellular signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

PKB Inhibition Prevents the Stimulatory Effect of Insulin on Glucose Transport and Protein Translocation but Not the Antilipolytic Effect in Rat Adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Phosphatidylinositol 3-kinase is a requirement for insulin-like growth factor I-induced differentiation, but not for mitogenesis, in fetal brown adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Okadaic acid inhibits insulin-induced glucose transport in fetal brown adipocytes in an Akt-independent and protein kinase C zeta-dependent manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Insulin-dependent regulation of Glut4 gene expression in ventricular cardiomyocytes: evidence for a direct effect on Glut4 transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

Insulin and insulin-like growth factor I up-regulate GLUT4 gene expression in fetal brown adipocytes, in a phosphoinositide 3-kinase-dependent manner.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902353-5

10.1016/S0014-5793(01)02353-5

7 January 2021

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DOI

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1 November 2017

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