Prostaglandin E2-EP4 receptor signalling promotes tumorigenic behaviour of HT-29 human colorectal cancer cells (Q42504729)

1 November 2017

Prostaglandin E2-EP4 receptor signalling promotes tumorigenic behaviour of HT-29 human colorectal cancer cells (English)

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1 November 2017

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G Hawcroft

1

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1 November 2017

C W S Ko

series ordinal

2

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1 November 2017

M A Hull

series ordinal

3

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1 November 2017

language of work or name

English

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publication date

20 November 2006

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1 November 2017

14

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inferred from page(s)

published in

Oncogene

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1 November 2017

26

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21

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1 November 2017

3006-3019

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210113

1 November 2017

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Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence

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Gastrin promotes human colon cancer cell growth via CCK-2 receptor-mediated cyclooxygenase-2 induction and prostaglandin E2 production

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EP(4) prostanoid receptor coupling to a pertussis toxin-sensitive inhibitory G protein

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Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

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Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

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Prostaglandin E2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases

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Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt.

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Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells

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Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer

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Prostaglandin E2 protects gastric mucosal cells from apoptosis via EP2 and EP4 receptor activation

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Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues

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Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells

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Paracrine cyclooxygenase-2-mediated signalling by macrophages promotes tumorigenic progression of intestinal epithelial cells

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Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

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Targeting prostaglandin E2 receptors as an alternative strategy to block cyclooxygenase-2-dependent extracellular matrix-induced matrix metalloproteinase-9 expression by macrophages

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Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation.

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Prostaglandin E2 increases growth and motility of colorectal carcinoma cells

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Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta

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Identifiers

DOI

10.1038/SJ.ONC.1210113

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Dimensions Publication ID

1 November 2017

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