Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology (Q42510074)

1 November 2017

Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology (English)

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1 November 2017

15

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1 November 2017

Salvatore J Orlando

1

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1 November 2017

Yolanda Santiago

2

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1 November 2017

Russell C DeKelver

3

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1 November 2017

Yevgeniy Freyvert

4

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1 November 2017

Elizabeth A Boydston

5

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1 November 2017

Erica A Moehle

6

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1 November 2017

Vivian M Choi

7

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1 November 2017

Sunita M Gopalan

8

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1 November 2017

Jacqueline F Lou

9

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1 November 2017

James Li

10

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1 November 2017

Jeffrey C Miller

11

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1 November 2017

Michael C Holmes

12

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1 November 2017

Philip D Gregory

13

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1 November 2017

Fyodor D Urnov

14

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1 November 2017

language of work or name

English

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publication date

8 June 2010

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1 November 2017

Nucleic Acids Research

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1 November 2017

38

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1 November 2017

15

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1 November 2017

e152

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Creative Commons Attribution-NonCommercial 2.5 Generic

1 November 2017

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2926620/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies.

1 reference

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Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

28 May 2018

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Directed evolution of recombinase specificity by split gene reassembly

28 May 2018

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Zinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modifications

28 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases.

28 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Precise targeted integration by a chimaeric transposase zinc-finger fusion protein.

28 May 2018

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Targeted chromosomal deletions in human cells using zinc finger nucleases

28 May 2018

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Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

28 May 2018

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CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

28 May 2018

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Synthesis of programmable integrases

28 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Increasing cloning possibilities using artificial zinc finger nucleases

28 May 2018

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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

28 May 2018

1 reference

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Capture of linear fragments at a double-strand break in yeast

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

An improved zinc-finger nuclease architecture for highly specific genome editing

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Targeted Sleeping Beauty transposition in human cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Conservative repair of a chromosomal double-strand break by single-strand DNA through two steps of annealing.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Employing epigenetics to augment the expression of therapeutic proteins in mammalian cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

28 May 2018

1 reference

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The mechanism of non-homologous end-joining: a synopsis of synapsis

28 May 2018

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Chromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Gene targeting in Arabidopsis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Promiscuous patching of broken chromosomes in mammalian cells with extrachromosomal DNA.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Capture of DNA sequences at double-strand breaks in mammalian chromosomes

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Design and selection of novel Cys2His2 zinc finger proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Coupled homologous and nonhomologous repair of a double-strand break preserves genomic integrity in mammalian cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Phosphorothioate oligodeoxynucleotides: what is their origin and what is unique about them?

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Transfer of YACs up to 2.3 Mb intact into human cells with polyethylenimine

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

A detailed study of the substrate specificity of a chimeric restriction enzyme.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

High-frequency illegitimate integration of transfected DNA at preintegrated target sites in a mammalian genome

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

In vivo biochemistry: physical monitoring of recombination induced by site-specific endonucleases.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

High frequency targeting of genes to specific sites in the mammalian genome

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Dependence of intrachromosomal recombination in mammalian cells on uninterrupted homology

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

End extension repair of introduced targeting vectors mediated by homologous recombination in mammalian cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Reexamination of Gene Targeting Frequency as a Function of the Extent of Homology between the Targeting Vector and the Target Locus

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

BAK and BAX deletion using zinc-finger nucleases yields apoptosis-resistant CHO cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Evolution of programmable zinc finger-recombinases with activity in human cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926620

Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ512

Patching broken chromosomes with extranuclear cellular DNA

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20530528

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High G/C content of cohesive overhangs renders DNA end joining Ku-independent

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20530528

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKQ512

1 reference

1 November 2017

1 reference

1 November 2017

PubMed publication ID

20530528

1 reference