Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis. (Q42519967)

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9 December 2019

title

Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis (English)

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9 December 2019

13

Mathias Jucker

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9 December 2019

12

Matthias Staufenbiel

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9 December 2019

author name string

Sonia Boncristiano

1

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9 December 2019

Michael E Calhoun

2

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9 December 2019

Peter H Kelly

3

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9 December 2019

Michelle Pfeifer

4

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9 December 2019

Luca Bondolfi

5

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9 December 2019

Martina Stalder

6

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9 December 2019

Amie L Phinney

7

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9 December 2019

Dorothee Abramowski

8

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9 December 2019

Christine Sturchler-Pierrat

9

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9 December 2019

Albert Enz

10

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9 December 2019

Bernd Sommer

11

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9 December 2019

language of work or name

English

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publication date

1 April 2002

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9 December 2019

published in

Journal of Neuroscience

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9 December 2019

volume

22

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9 December 2019

page(s)

3234-3243

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9 December 2019

issue

8

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A rapid radiochemical method for the determination of choline acetyltransferase

9 December 2019

cites work

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Activation of protein kinase C inhibits cellular production of the amyloid beta-protein

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Evolution of Alzheimer's disease-related cytoskeletal changes in the basal nucleus of Meynert.

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Cholinergic innervation of mouse forebrain structures

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Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

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In vivo regulation of amyloid precursor protein secretion in rat neocortex by cholinergic activity

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Topographic analysis of the innervation of the rat neocortex and hippocampus by the basal forebrain cholinergic system

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Essential role of neocortical acetylcholine in spatial memory

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Expression of the neural adhesion molecule L1 in the deafferented dentate gyrus

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Acetylcholinesterase-positive fiber deafferentation and cell shrinkage in the septohippocampal pathway of aged amyloid precursor protein london mutant transgenic mice

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Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice.

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Beta-amyloid peptides as direct cholinergic neuromodulators: a missing link?

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Microglial response to amyloid plaques in APPsw transgenic mice.

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beta-Amyloid(1-42) peptide directly modulates nicotinic receptors in the rat hippocampal slice.

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Correlation of cortical cholinergic and GABA deficits with quantitative neuropathological findings in senile dementia.

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Alzheimer's disease: is the decrease of the cholinergic innervation of the hippocampus related to intrinsic hippocampal pathology?

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Ultrastructural localization of acetylcholinesterase in neurofibrillary tangles, neuropil threads and senile plaques in aged and Alzheimer's brain

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Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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Progressive age-related impairment of cognitive behavior in APP23 transgenic mice.

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Neocortical infarction in subhuman primates leads to restricted morphological damage of the cholinergic neurons in the nucleus basalis of Meynert

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Animal models of Alzheimer's disease: experimental cholinergic denervation

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12 December 2020

New stereological methods for counting neurons

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Cholinergic activation of phosphoinositide signaling is impaired in Alzheimer's disease brain.

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12 December 2020

Cholinergic function and intellectual decline in Alzheimer's disease

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12 December 2020

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

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12 December 2020

Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains

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12 December 2020

Some new, simple and efficient stereological methods and their use in pathological research and diagnosis.

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12 December 2020

Estimating neuron dendritic length in 3D from total vertical projections and from vertical slices.

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12 December 2020

Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

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12 December 2020

Convergent cholinergic activities in aging and Alzheimer's disease.

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12 December 2020

Decrease of neocortical choline acetyltransferase after lesion of the globus pallidus in the rat

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12 December 2020

A brain regional analysis of morphologic and cholinergic abnormalities in Alzheimer's disease.

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12 December 2020

Effect of alkalizing agents on the processing of the beta-amyloid precursor protein.

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12 December 2020

An Immunological Study of Rat Acetylcholinesterase: Comparison with Acetylcholinesterases from Other Vertebrates

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12 December 2020

Survival and plasticity of basal forebrain cholinergic systems in mice transgenic for presenilin-1 and amyloid precursor protein mutant genes

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12 December 2020

Immunocytochemical distribution of peptidergic and cholinergic fibers in the human amygdala: their depletion in Alzheimer's disease and morphologic alteration in non-demented elderly with numerous senile plaques.

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12 December 2020

Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy.

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12 December 2020

The cholinergic hypothesis of geriatric memory dysfunction

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Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

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A modified histochemical technique to visualize acetylcholinesterase-containing axons.

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Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease.

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The cholinergic deficit coincides with Abeta deposition at the earliest histopathologic stages of Alzheimer disease.

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A new and rapid colorimetric determination of acetylcholinesterase activity

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Pharmacological drug treatment of Alzheimer disease: the cholinergic hypothesis revisited.

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Colocalization of cholinesterases with beta amyloid protein in aged and Alzheimer's brains.

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Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group

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12 December 2020

Improved electrophoretic separation and immunoblotting of beta-amyloid (A beta) peptides 1-40, 1-42, and 1-43.

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12 December 2020

Tau protein and the neurofibrillary pathology of Alzheimer's disease

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12 December 2020

Retrograde changes in cholinergic neurons in the basal forebrain of the rat following cortical damage

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12 December 2020

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

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12 December 2020

Amyloid beta-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain.

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12 December 2020

Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation

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12 December 2020

Cholinergic deafferentation of the rabbit cortex: a new animal model of Abeta deposition

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12 December 2020

Electrophoretic Separation of βA4 Peptides (1–40) and (1–42)

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12 December 2020

Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits.

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12 December 2020

An unbiased method for estimation of total epidermal nerve fibre length

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12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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12 December 2020

Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

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12 December 2020

Cell loss and shrinkage in the nucleus basalis Meynert complex in Alzheimer's disease

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12 December 2020

Relationship between plaques, tangles, and loss of cortical cholinergic fibers in Alzheimer disease

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12 December 2020

Protofibrils, the unifying toxic molecule of neurodegenerative disorders?

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12 December 2020

Cholinesterases in the amyloid angiopathy of Alzheimer's disease

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12 December 2020

Cholinergic activity and amyloid precursor protein metabolism

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12 December 2020

Neurofibrillary degeneration and cell loss in the nucleus basalis in comparison to cortical Alzheimer pathology.

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12 December 2020

Association of microglia with amyloid plaques in brains of APP23 transgenic mice

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12 December 2020

Brain trauma in aged transgenic mice induces regression of established abeta deposits

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12 December 2020

Neuron loss in APP transgenic mice

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12 December 2020

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

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12 December 2020

Amyloid, the presenilins and Alzheimer's disease

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12 December 2020

Neurochemical activities in human temporal lobe related to aging and Alzheimer-type changes

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12 December 2020

Expression of APP in transgenic mice: a comparison of neuron-specific promoters.

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12 December 2020

Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities.

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12 December 2020

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12 December 2020

Cortical projection patterns of the medial septum-diagonal band complex

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12 December 2020

Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice.

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12 December 2020

The systems-level organization of cholinergic innervation in the human cerebral cortex and its alterations in Alzheimer's disease.

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12 December 2020

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

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12 December 2020

Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.

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12 December 2020

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12 December 2020

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

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12 December 2020

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

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12 December 2020

10.1523/JNEUROSCI.22-08-03234.2002

Identifiers

DOI

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9 December 2019

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9 December 2019

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