Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome (Q42527629)

1 November 2017

Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome (English)

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1 November 2017

3

Lynn A Hyde

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1 November 2017

Ann-Charlotte E Granholm

1

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1 November 2017

Kerstin A Ford

2

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1 November 2017

Heather A Bimonte

4

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1 November 2017

Christopher L Hunter

5

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1 November 2017

Matt Nelson

6

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1 November 2017

David Albeck

7

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1 November 2017

Linda A Sanders

8

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1 November 2017

Elliott J Mufson

9

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1 November 2017

Linda S Crnic

10

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1 November 2017

language of work or name

English

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publication date

1 November 2002

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1 November 2017

Physiology & Behavior

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1 November 2017

77

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1 November 2017

2-3

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1 November 2017

371-385

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Alzheimer's disease: etiologies, pathophysiology, cognitive reserve, and treatment opportunities

1 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Etiology and pathogenesis of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

New order from neurological disorders

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https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

The cholinergic system in Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

The cognitive psychopharmacology of Alzheimer's disease: focus on cholinergic systems

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https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor.

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https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Systemic administration of a nerve growth factor conjugate reverses age-related cognitive dysfunction and prevents cholinergic neuron atrophy.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Down syndrome phenotypes: the consequences of chromosomal imbalance

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Alzheimer-like cholinergic deficiency in Down syndrome

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https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Abnormalities of the nucleus basalis in Down's syndrome

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https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Reduction in TrkA-immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

A mouse model for Down syndrome exhibits learning and behaviour deficits.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

A behavioral assessment of Ts65Dn mice: a putative Down syndrome model.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Impaired short- and long-term memory in Ts65Dn mice, a model for Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Characterization of sensorimotor performance, reproductive and aggressive behaviors in segmental trisomic 16 (Ts65Dn) mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Behavioral assessment of the Ts65Dn mouse, a model for Down syndrome: altered behavior in the elevated plus maze and open field

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Spatial memory deficits in segmental trisomic Ts65Dn mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Menopause in women with learning disabilities.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Effect of menopause on cognitive performance in women with Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Cellular and molecular basis of estrogen's neuroprotection. Potential relevance for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Post-menopausal estrogen deprivation and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Oestrogen and nerve growth factor - neuroprotection and repair in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estrogen as a growth factor to central nervous cells. Estrogen treatment promotes development of acetylcholinesterase-positive basal forebrain neurons transplanted in the anterior eye chamber

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Inhibition of dendritic spine induction on hippocampal CA1 pyramidal neurons by a nonsteroidal estrogen antagonist in female rats

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

The effects of ovariectomy and estrogen replacement on trkA and choline acetyltransferase mRNA expression in the basal forebrain of the adult female Sprague-Dawley rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estrogen modulates spontaneous alternation and the cholinergic phenotype in the basal forebrain

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Identification of a nonsense mutation in the rod photoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Plasma Estrogens in Pregnant and Postpartum Mares2

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

A computer-aided procedure for measuring swim rotation

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

New stereological methods for counting neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Acute application of NGF increases the firing rate of aged rat basal forebrain neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

An enzyme-linked immunoassay for nerve growth factor (NGF): a tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Lactoferrin expression in the mouse reproductive tract during the natural estrous cycle: correlation with circulating estradiol and progesterone.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Motor dysfunction in a mouse model for Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Motor learning in Ts65Dn mice, a model for Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neurotransmitters.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estrogen affects performance of ovariectomized rats in a two-choice water-escape working memory task.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

In mice tonic estrogen replacement therapy improves non-spatial and spatial memory in a water maze task.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estrogen enhances performance of female rats during acquisition of a radial arm maze

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estradiol facilitates performance as working memory load increases.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estrogen replacement therapy in older women. Comparisons between Alzheimer's disease cases and nondemented control subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estrogenic effects on memory in women

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore Longitudinal Study of Aging

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease: results of a placebo-controlled, double-blind, pilot study.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Is there a role for estrogen replacement therapy in the prevention and treatment of dementia?

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Endogenous estrogen levels and Alzheimer's disease among postmenopausal women.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Alzheimer's disease and down syndrome: from meiosis to dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Age at onset of dementia and age of menopause in women with Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Effects of estrogen replacement on the relative levels of choline acetyltransferase, trkA, and nerve growth factor messenger RNAs in the basal forebrain and hippocampal formation of adult rats

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estrogen and nerve growth factor-related systems in brain. Effects on basal forebrain cholinergic neurons and implications for learning and memory processes and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

1 reference

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Nontoxic amyloid beta peptide 1-42 suppresses acetylcholine synthesis. Possible role in cholinergic dysfunction in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Cholinotoxic effects of beta-amyloid (1-42) peptide on cortical projections of the rat nucleus basalis magnocellularis

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Administration of amyloid beta-peptides in the rat medial septum causes memory deficits: reversal by SR 57746A, a non-peptide neurotrophic compound.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

The female sex hormone oestrogen as neuroprotectant: activities at various levels

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2802%2900884-3

7 January 2021

10.1016/S0031-9384(02)00884-3

Identifiers

DOI

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1 November 2017

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