Axonal transport deficit in a KIF5A( -/- ) mouse model (Q42535695)

1 November 2017

Axonal transport deficit in a KIF5A( -/- ) mouse model (English)

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1 November 2017

3

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1 November 2017

4

Ludger Schöls

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1 November 2017

Kathrin N Karle

1

1 reference

PMCID

3332386

1 November 2017

Diana Möckel

series ordinal

2

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1 November 2017

1 April 2012

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1 November 2017

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1 November 2017

13

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1 November 2017

2

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1 November 2017

169-179

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PMCID

3332386

describes a project that uses

1 November 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3332386/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1007/s10048-012-0324-y

0 references

cites work

Hereditary spastic paraplegias: membrane traffic and the motor pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Kinesin-1/Hsc70-dependent mechanism of slow axonal transport and its relation to fast axonal transport

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Traffic control: regulation of kinesin motors.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Genetics of motor neuron disorders: new insights into pathogenic mechanisms

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Tight functional coupling of kinesin-1A and dynein motors in the bidirectional transport of neurofilaments

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Kinesin superfamily motor proteins and intracellular transport

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Consequences of motor copy number on the intracellular transport of kinesin-1-driven lipid droplets

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Conventional kinesin holoenzymes are composed of heavy and light chain homodimers

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Effect of spastic paraplegia mutations in KIF5A kinesin on transport activity

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Hereditary spastic paraplegias: an update

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Nitric oxide impairs mitochondrial movement in cortical neurons during hypoxia

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Mutation in KIF5A can also cause adult-onset hereditary spastic paraplegia

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Hither and yon: a review of bi-directional microtubule-based transport

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Tubulin and CRMP-2 complex is transported via Kinesin-1

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Bidirectional transport along microtubules.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Expression of phosphatidylinositol (4,5) bisphosphate-specific pleckstrin homology domains alters direction but not the level of axonal transport of mitochondria.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Science in motion: common molecular pathological themes emerge in the hereditary spastic paraplegias

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10)

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Oligomeric tubulin in large transporting complex is transported via kinesin in squid giant axons

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

KIF5C, a novel neuronal kinesin enriched in motor neurons

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Hereditary "pure" spastic paraplegia: a clinical and genetic study of 22 families

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Classification of the hereditary ataxias and paraplegias

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Complicated forms of autosomal dominant hereditary spastic paraplegia are frequent in SPG10.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Mitochondrial trafficking to synapses in cultured primary cortical neurons.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Building complexity: an in vitro study of cytoplasmic dynein with in vivo implications

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Nerve growth factor signaling regulates motility and docking of axonal mitochondria.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

Axonal mitochondrial transport and potential are correlated

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

A Missense Mutation in the Coiled-Coil Domain of the KIF5A Gene and Late-Onset Hereditary Spastic Paraplegia

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10048-012-0324-Y

Kinesin-1 plays a role in transport of SNAP-25 to the plasma membrane

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332386

A novel KIF5A/SPG10 mutation in spastic paraplegia associated with axonal neuropathy

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22466687

12 December 2020

inferred from PubMed ID database lookup

The role of Kinesin neck linker and neck in velocity regulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22466687

12 December 2020

inferred from PubMed ID database lookup

SPG10 is a rare cause of spastic paraplegia in European families

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22466687

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S10048-012-0324-Y

1 reference

1 November 2017

1 reference

1 November 2017

1 reference

PMCID

3332386