Biochemical characterization of HIV-1 reverse transcriptases encoding mutations at amino acid residues 161 and 208 involved in resistance to phosphonoformate. (Q42536157)

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scientific article published on December 1998

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English	Biochemical characterization of HIV-1 reverse transcriptases encoding mutations at amino acid residues 161 and 208 involved in resistance to phosphonoformate.	scientific article published on December 1998

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11 December 2019

Biochemical characterization of HIV-1 reverse transcriptases encoding mutations at amino acid residues 161 and 208 involved in resistance to phosphonoformate (English)

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11 December 2019

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11 December 2019

Enzo Tramontano

1

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11 December 2019

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J W Mellors

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11 December 2019

M Putzolu

4

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11 December 2019

H Z Bazmi

5

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11 December 2019

P La Colla

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11 December 2019

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1 December 1998

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11 December 2019

Biochemical Pharmacology

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11 December 2019

56

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11 December 2019

12

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11 December 2019

1583-1589

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11 December 2019

Antiviral effects of phosphonoformate (PFA, foscarnet sodium).

1 reference

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Foscarnet decreases human immunodeficiency virus RNA.

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Mechanism of action of foscarnet against viral polymerases

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7 January 2021

Isolation of Foscarnet-Resistant Human Cytomegalovirus Patterns of Resistance and Sensitivity to Other Antiviral Drugs

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7 January 2021

Novel mutations in reverse transcriptase of human immunodeficiency virus type 1 reduce susceptibility to foscarnet in laboratory and clinical isolates

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7 January 2021

Characterisation of foscarnet-resistant strains of human immunodeficiency virus type 1.

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7 January 2021

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

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7 January 2021

HIV-1 reverse transcriptase inhibition by a dipyridodiazepinone derivative: BI-RG-587

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7 January 2021

Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase

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7 January 2021

Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate. Implications for multiple drug resistance.

1 reference

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7 January 2021

Metal activation of synthetic and degradative activities of phi 29 DNA polymerase, a model enzyme for protein-primed DNA replication

1 reference

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7 January 2021

Human immunodeficiency virus type-1 reverse transcriptase. Contribution of Met-184 to binding of nucleoside 5'-triphosphate

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7 January 2021

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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7 January 2021

Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine

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7 January 2021

Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors.

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7 January 2021

HIV resistance to reverse transcriptase inhibitors

1 reference

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7 January 2021

Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recov

1 reference

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7 January 2021

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10.1016/S0006-2952(98)00206-8

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9973178%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9973178%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

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