Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin (Q42573161)

2 November 2017

Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin (English)

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2 November 2017

9

Huib Ovaa

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2 November 2017

8

Titia K Sixma

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2 November 2017

Farid El Oualid

1

1 reference

2 November 2017

Remco Merkx

2

1 reference

2 November 2017

Reggy Ekkebus

3

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2 November 2017

Dharjath S Hameed

4

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2 November 2017

Judith J Smit

5

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2 November 2017

Annemieke de Jong

6

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2 November 2017

Henk Hilkmann

7

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2 November 2017

language of work or name

English

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publication date

1 December 2010

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Angewandte Chemie International Edition

2 November 2017

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volume

49

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2 November 2017

10149-10153

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2 November 2017

52

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Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

2 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Origin and function of ubiquitin-like proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Modification of proteins by ubiquitin and ubiquitin-like proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Synthesis, structural and biological studies of ubiquitin mutants containing (2S, 4S)-5-fluoroleucine residues strategically placed in the hydrophobic core

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

A proteomics approach to understanding protein ubiquitination

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Chemically synthesized ubiquitin extension proteins detect distinct catalytic capacities of deubiquitinating enzymes.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Synthetic, structural and biological studies of the ubiquitin system: the total chemical synthesis of ubiquitin

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Synthesis of K48-linked diubiquitin using dual native chemical ligation at lysine

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Protecting group variations of delta-mercaptolysine useful in chemical ubiquitylation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Dual native chemical ligation at lysine

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Functional ubiquitin conjugates with lysine-epsilon-amino-specific linkage by thioether ligation of cysteinyl-ubiquitin peptide building blocks.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Controlled synthesis of polyubiquitin chains

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Expediting the Fmoc solid phase synthesis of long peptides through the application of dimethyloxazolidine dipeptides

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Synthetic, structural and biological studies of the ubiquitin system: synthesis and crystal structure of an analogue containing unnatural amino acids.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

An enzyme with ubiquitin carboxy-terminal esterase activity from reticulocytes

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3021723

Insights into the mechanism and catalysis of the native chemical ligation reaction

16 August 2018

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12 December 2020

Chemoenzymatic ubiquitination of artificial substrates

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12 December 2020

A sensitive fluorescence intensity assay for deubiquitinating proteases using ubiquitin-rhodamine110-glycine as substrate

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12 December 2020

Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation

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12 December 2020

Generation of site-specific and enzymatically stable conjugates of recombinant proteins with ubiquitin-like modifiers by the Cu(I)-catalyzed azide-alkyne cycloaddition

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12 December 2020

Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes

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12 December 2020

Ubiquitin: preparative chemical synthesis, purification and characterization

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12 December 2020

Identifiers

DOI

10.1002/ANIE.201005995

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2 November 2017

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2 November 2017

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