Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart (Q42593363)

3 November 2017

Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart (English)

1 reference

3 November 2017

8

Jason K Kim

1 reference

3 November 2017

Hwi Jin Ko

1

1 reference

3 November 2017

Zhiyou Zhang

2

1 reference

3 November 2017

Dae Young Jung

3

1 reference

3 November 2017

John Y Jun

4

1 reference

3 November 2017

Zhexi Ma

5

1 reference

3 November 2017

Kelly E Jones

6

1 reference

3 November 2017

Sook Y Chan

7

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3 November 2017

language of work or name

English

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publication date

18 August 2009

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3 November 2017

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3 November 2017

58

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3 November 2017

2536-2546

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3 November 2017

11

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

3 November 2017

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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28 May 2018

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Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase

28 May 2018

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28 May 2018

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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

28 May 2018

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28 May 2018

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Macrophage-secreted factors induce adipocyte inflammation and insulin resistance

28 May 2018

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CCR2 modulates inflammatory and metabolic effects of high-fat feeding

28 May 2018

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AMP-activated protein kinase: a key stress signaling pathway in the heart

28 May 2018

1 reference

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Inflammation, stress, and diabetes

28 May 2018

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Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

28 May 2018

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Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling

28 May 2018

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

28 May 2018

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Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

28 May 2018

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Interleukin-6 induces cellular insulin resistance in hepatocytes

28 May 2018

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SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

28 May 2018

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Muscle-derived interleukin-6: mechanisms for activation and possible biological roles

28 May 2018

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Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction.

28 May 2018

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Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

28 May 2018

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28 May 2018

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The hormone resistin links obesity to diabetes

30 September 2018

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Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes

28 May 2018

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Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

28 May 2018

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SOCS-3 is an insulin-induced negative regulator of insulin signaling

28 May 2018

1 reference

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Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association

28 May 2018

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Regulation of energy substrate metabolism in the diabetic heart

28 May 2018

1 reference

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Abnormal mechanical function in diabetes: relationship to altered myocardial carbohydrate/lipid metabolism

28 May 2018

1 reference

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Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC

28 May 2018

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

28 May 2018

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The diabetic heart: metabolic causes for the development of a cardiomyopathy

28 May 2018

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Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart.

28 May 2018

1 reference

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Exercise increases SOCS-3 expression in rat skeletal muscle: potential relationship to IL-6 expression.

16 August 2018

1 reference

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Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice

16 August 2018

1 reference

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Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver

16 August 2018

1 reference

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Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768176

Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768176

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768176

Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768176

Interleukin-6-deficient mice develop mature-onset obesity

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768176

Myocardial glucose metabolism in noninsulin-dependent diabetes mellitus patients evaluated by FDG-PET.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768176

Molecular analysis of insulin resistance in isolated ventricular cardiomyocytes of obese Zucker rats

16 August 2018

1 reference

12 December 2020

Adiposity elevates plasma MCP-1 levels leading to the increased CD11b-positive monocytes in mice

1 reference

12 December 2020

Defective energy metabolism of the heart in diabetes

1 reference

12 December 2020

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

1 reference

12 December 2020

Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis

1 reference

12 December 2020

IL-6 increases muscle insulin sensitivity only at superphysiological levels

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB08-1361

1 reference

3 November 2017

1 reference

3 November 2017

1 reference