Pharmacological characterization of MP349, a novel 5-HT1A-receptor antagonist with anxiolytic-like activity, in mice and rats (Q42601434)

3 November 2017

title

Pharmacological characterization of MP349, a novel 5-HT1A-receptor antagonist with anxiolytic-like activity, in mice and rats (English)

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3 November 2017

4

Ewa Chojnacka-Wójcik

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Krystyna Gołembiowska

series ordinal

3

object named as

Krystyna Gołembiowska

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3 November 2017

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Anna Wesołowska

1

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3 November 2017

Maria H Paluchowska

series ordinal

2

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3 November 2017

Ewa Chojnacka-Wójcik

series ordinal

4

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3 November 2017

publication date

1 April 2003

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Journal of Pharmacy and Pharmacology

3 November 2017

published in

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3 November 2017

volume

55

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3 November 2017

issue

4

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3 November 2017

page(s)

533-543

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Role of calcium channels in effects of antidepressant drugs on responsiveness to pain

3 November 2017

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Selective activation of 5HT1A receptors induces lower lip retraction in the rat.

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Depletion of brain serotonin differently affects behaviors induced by 5HT1A, 5HT1C, and 5HT2 receptor activation in rats

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Anxiolytic-like profile of p-MPPI, a novel 5HT1A receptor antagonist, in the murine elevated plus-maze.

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5-HT1A receptor full and partial agonists and 5-HT2C (but not 5-HT3) receptor antagonists increase rates of punished responding in rats.

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Effects of 5-HT1A receptor ligands on a safety signal withdrawal procedure of conflict in the rat.

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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On the elevated plus-maze the anxiolytic-like effects of the 5-HT(1A) agonist, 8-OH-DPAT, but not the anxiogenic-like effects of the 5-HT(1A) partial agonist, buspirone, are blocked by the 5-HT1A antagonist, WAY 100635.

21 January 2018

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The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats. A comparison with other an

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Modification of the anxiolytic action of 5-HT1A compounds by GABA-benzodiazepine agents in rats.

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WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A receptors

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Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

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Administration of 8-hydroxy-2-(Di-n-propylamino)tetralin in raphe nuclei dorsalis and medianus reduces serotonin synthesis in the rat brain: differences in potency and regional sensitivity

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Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated

21 January 2018

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Interaction of GABA and serotonin in the anxiolytic action of diazepam and serotonergic anxiolytics

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Anxiolytic-like effect of (S)-WAY 100135, a 5-HT1A receptor antagonist, in the murine elevated plus-maze test.

21 January 2018

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21 January 2018

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The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-propylamino)tetralin in the rat.

21 January 2018

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Preclinical pharmacology of B-20991, a 5-HT1A receptor agonist with anxiolytic activity

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21 January 2018

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21 January 2018

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The role of hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptors in the anticonflict activity of beta-adrenoceptor antagonists

21 January 2018

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Somatodendritic 5-HT1A receptors are critically involved in the anxiolytic effects of 8-OH-DPAT

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1211/0022357021017

1 reference

release_7y6e3sh5bfb4dmte5f4z5q2e5u

3 November 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/7y6e3sh5bfb4dmte5f4z5q2e5u

mapped directly with Wikidata item

24 November 2022

based on heuristic

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